ArticleJournal of racial and ethnic health disparities2026
Sickle Cell Disease in Eastern Uttar Pradesh, India: Sociodemographic and Clinical Profile from a Previously Undocumented Area.
Article in Journal of racial and ethnic health disparities, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSickle cell disease (SCD) is a significant public health concern in India, with varying prevalence across regions. Data from eastern Uttar Pradesh remains scarce. Aim of the study was to describe the sociodemographic and clinical profile of patients with SCD in this previously undocumented area.
methodsA cross-sectional study was conducted among diagnosed SCD patients attending tertiary care healthcare facility in Eastern Uttar Pradesh. Sociodemographic variables and clinical features (age at start of symptoms and diagnosis, frequency of pain episodes/crises, complications, and treatment modalities) were recorded and analyzed.
resultsOne hundred and twenty patients (90 HbSS; 30 HbSβ) were included in the study. Majority (65%) were from Sonbhadra district (Uttar Pradesh) followed by Gadhwa and Palamu districts (Jharkhand). Hindu and muslim patients comprised 58.3% and 41.7% respectively. Other backward castes were maximally represented (58.4%) followed by scheduled tribes (21.7%), general (16.7%) and scheduled castes (3.3%). Mean age was 9.13 ± 4.08 years with male to female ratio of 2.5:1. Painful crises was experienced by 71.1% patients. Splenomegaly was present in (104) 86.7% patients. Mean HbF% was 17.71 ± 17.51 vs. 25.69 ± 9.23 in HbSS and HbSβ groups. HbF% had no correlation with frequency and intensity of pain episodes or blood transfusions. Frequency of pain episodes had positive correlation with frequency of blood transfusions. Hydroxyurea therapy was underutilized.
conclusionThis study provides the first detailed account of SCD in Eastern Uttar Pradesh, highlighting demographic, ethnic and clinical profile with gaps in clinical management. Findings underscore the need for targeted health interventions in this underserved region.
Indexed as
Identifiers
41495554What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.