Evidence map›Paper›PMID 41495529›Full record

ArticleMikrochimica acta2026

Simultaneous on-site screening of four prohibited anti-inflammatory drugs in herbal tea by a multiplex lateral flow immunoassay.

Jiajun Xu, Maner Chen, Hengye Zhang, Kai Chen, Chengsheng Hu, Hui Liu, Hongtao Lei, Tian Guan

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Jiajun XuGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, No.483 Wushan Road, Tianhe District, Guangzhou, 510642, China.
Maner ChenGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, No.483 Wushan Road, Tianhe District, Guangzhou, 510642, China.
Hengye ZhangGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, No.483 Wushan Road, Tianhe District, Guangzhou, 510642, China.
Kai ChenGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, No.483 Wushan Road, Tianhe District, Guangzhou, 510642, China.
Chengsheng HuGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, No.483 Wushan Road, Tianhe District, Guangzhou, 510642, China.
Hui LiuGuangdong Testing Institute of Product Quality Supervision, No. 10 Science Avenue, Huangpu District, Guangzhou, 510670, China.
Hongtao LeiGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, No.483 Wushan Road, Tianhe District, Guangzhou, 510642, China. hongtao@scau.edu.cn.
Tian GuanGuangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, No.483 Wushan Road, Tianhe District, Guangzhou, 510642, China. guantian@scau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A rapid and sensitive multiplex lateral flow immunoassay (LFIA) was developed using high-brightness latex microspheres (LMs), which can simultaneously detect paracetamol, phenacetin, antipyrine, and prednisone acetate in herbal tea within 10 min. Under optimized experimental conditions, this LMs-LFIA can detect the four analytes at concentrations as low as 6.4 ng/mL, 0.38 ng/mL, 0.026 ng/mL, and 4.6 ng/mL, with low cut-off values (200 ng/mL, 200 ng/mL, 160 ng/mL, 160 ng/mL, respectively). Besides, this work demonstrated high specificity (no cross-interferences), good reproducibility (˂7.50%), acceptable stability (60 days) and high recoveries (90.2% − 118.1%) in spiked herbal samples. Importantly, in the blind sample analysis, of the developed LMs-LFIA showed good agreement with the validated LC-MS/MS method, suggesting high accuracy and practicability. This work provides a robust tool for highly efficient monitoring of common illegally added anti-inflammatory drugs in herbal teas.

Indexed as

Anti-Inflammatory AgentsTeas, HerbalAcetaminophenAntipyrineImmunoassayLimit of DetectionMicrospheresPrednisoneAcetaminophenAnti-Inflammatory AgentsAntipyrinePrednisoneTeas, HerbalAnti-inflammatory drugsHerbal teaIllegally added drugsLateral flow immunoassayMultiplex gray scale detection

Identifiers

PMID41495529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.