Evidence map›Paper›PMID 41495490›Full record

ArticleJournal of animal science2026

Evaluation of calcium β-hydroxy-β-methylbutyrate on performance of Bos indicus-influenced cattle in a subtropical environment.

Rodrigo D L Pacheco, Jéssica O Gusmão, Alex S Maia, Pedro H P Terêncio, João P S T Bastos, Ricardo Ávila, Bradley J Johnson, Victor P C Campanelli, Vinícius F C Fonsêca, Gustavo A B Moura and 2 more

Abstract read
In one paragraph

Article in Journal of animal science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rodrigo D L PachecoAgro-Pastoril Paschoal Campanelli, Research Center, Altair, São Paulo, 15430-000, Brazil.
Jéssica O GusmãoAgro-Pastoril Paschoal Campanelli, Research Center, Altair, São Paulo, 15430-000, Brazil.
Alex S MaiaInnovation in Sustainability in Animal Biometeorology, Animal Biometeorology Laboratory, São Paulo State University, 14844-900, Brazil.
Pedro H P TerêncioAgro-Pastoril Paschoal Campanelli, Research Center, Altair, São Paulo, 15430-000, Brazil.
João P S T BastosInfinity Consultoria, Rua José Joaquim Francisco, Uberlândia/MG, 06541-970, Brazil.
Ricardo ÁvilaMaravedi Services and Consulting Company, São Paulo, 02441-000, Brazil.
Bradley J JohnsonDepartment of Animal and Food Sciences, Texas Tech University, Lubbock, TX 79409.
Victor P C CampanelliAgro-Pastoril Paschoal Campanelli, Research Center, Altair, São Paulo, 15430-000, Brazil.
Vinícius F C FonsêcaInnovation in Sustainability in Animal Biometeorology, Animal Biometeorology Laboratory, São Paulo State University, 14844-900, Brazil.
Gustavo A B MouraInnovation in Sustainability in Animal Biometeorology, Animal Biometeorology Laboratory, São Paulo State University, 14844-900, Brazil.ORCID 0000-0001-7278-819X
Rafael Da C CervieriNutribeef Consulting, Botucatu, São Paulo, 18609-660, Brazil.
John C FullerMetabolic Technologies, Missoula, MT 59802.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-Hydroxy-β-methylbutyrate (HMB), a metabolite of leucine, increases both protein synthesis and lipolysis, immune function, and overall health in both humans and animals. Previous cattle studies have shown that HMB, fed as calcium HMB (CaHMB), can minimize stress responses and improve meat quality. The objective of the present study was to investigate the effect of feeding CaHMB in a subtropical feedlot on performance of Nellore (Bos indicus) bulls. A total of 3,520 bulls (64 pens; 55 animals per pen) were studied with four levels of CaHMB (0 [control, CON], 3, 5, or 7 g per head per day) and half the pens had shade access (SH), and half did not in a split-plot experimental design. Diets containing CaHMB were fed during three phases of the study, adaptation, growth, and finishing. There were no CaHMB × SH interactions observed for any variable measured. However, adjusted final body weight (FBW) tended to increase in CaHMB-treated bulls up to 5.8 kg in bulls fed 3 g per day (linear P < 0.07). Additionally, adjusted average daily gain (ADG) and carcass ADG were also increased with 3 g per day CaHMB by 3.2% and 2.6%, respectively, when compared with CON (linear P < 0.04). Bulls fed CaHMB tended to have increased hot carcass weight (HCW) by up to 3.4 kg in bulls fed 3 g CaHMB per day and a 0.36% increase in dressing percentage (DP) (linear P < 0.07 and 0.09, respectively). No differences were observed in dry matter intake (DMI) during any of the feeding periods. No significant differences were observed in gain:feed. Of major importance to the subtropical environment, 34% of the days were considered hot to very hot with the comfort level (InCI) >0.45 on a 0 to 1.0 scale. In conclusion, supplementing Bos indicus bulls with CaHMB resulted in improved growth performance and carcass yield.

Indexed as

ValeratesAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsCattleDietDietary SupplementsMaleTropical Climatebeta-hydroxyisovaleric acidValeratesBos indicusCaHMBcattleperformanceshadesubtropical environment

Identifiers

PMID41495490
PMCPMC12884845

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.