Evidence map›Paper›PMID 41495403›Full record

ArticleNature medicine2026

Interpersonal conflicts, social media use and depression associated with protests.

Jian Shi, Candi M C Leung, Roujia Chen, Xiao Xiao, Francis P Flores, Ke Ning, Tiffany S W Ma, Solomon B K Wong, Corine S M Wong, Yoona Kim and 3 more

Abstract read
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In one paragraph

Article in Nature medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jian Shi *School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Candi M C Leung *School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Roujia ChenSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Xiao XiaoSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Francis P FloresSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Ke NingResearch Division, Institute of Mental Health, Singapore, Singapore.
Tiffany S W MaSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Solomon B K WongSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Corine S M WongSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID 0000-0003-3363-1004
Yoona KimSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID 0000-0003-3473-8516
Ichiro KawachiDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Gabriel M LeungSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID 0000-0002-2503-6283
Michael Y NiSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China. nimy@hku.hk.ORCID 0000-0002-1217-5858

Funding

Research Grants Council, University Grants Committee (RGC, UGC) HKU 17609818Research Grants Council, University Grants Committee (RGC, UGC) HKU 17609923
6 · The paper itself

Abstract

Globally, the number of social protests has increased in the 21st century, and these have been associated with mental health consequences. Here we examined how interpersonal conflicts and social media use are associated with depression in a 15-year prospective cohort of 1,044-17,000 adults, assessed at 23 time points before, during and after two major protests in Hong Kong. During the 2019 social unrest, 32.4% of participants reported conflicts with family, friends, colleagues or strangers, higher than during the 2014 Occupy Central period (11.6-27.5%) and the following year (6.0-10.3%). Interpersonal conflicts were associated with depressive outcomes, with long-term associations persisting over 13 years (odds ratio (OR) = 1.49, 95% CI = 1.12-1.97). During the 2019 social unrest, almost half of adults spent ≥1 h per day on politics-related content on social media (47.4%), television (46.5%) and newspapers and radio (42.1%). Only heavy social media use (≥2 h per day) was positively associated with interpersonal conflicts and depression. Our findings suggest that protests are associated with depression in the long term as a result of sustained interpersonal conflicts, while heavy social media use may contribute to the association. To mitigate this impact, it is vital to provide social support to improve mental health of the affected individuals.

Indexed as

Conflict, PsychologicalDepressionInterpersonal RelationsSocial MediaAdultFemaleHong KongHumansMaleMental HealthMiddle AgedProspective StudiesYoung Adult

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.