Evidence map›Paper›PMID 41495296›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

CUBD classification: A novel disc height-based grading system for uncovertebral joint degeneration with validated reliability and clinical correlations.

Chang Liu, Jiang Long, Xue Leng, Ya Ning, Bo Huang

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Chang LiuArmy Medical University, Shapingba, Chongqing, China. liuchangsp@tmmu.edu.cn.
Jiang LongArmy Medical University, Shapingba, Chongqing, China.
Xue LengArmy Medical University, Shapingba, Chongqing, China.
Ya NingArmy Medical University, Shapingba, Chongqing, China.
Bo HuangArmy Medical University, Shapingba, Chongqing, China. spinehb@tmmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to investigate a novel classification system for uncovertebral joint (UVJs) degeneration based on CT scans, referred to as the CUBD (Classification of Uncovertebral Joint Degeneration Based on Disc Height) system. Additionally, we assessed its reliability and internal consistency.

methodsQuantitative assessment of CUBD classification was performed at C3-C7 levels using cervical computed tomography (CT), with concurrent evaluation of key degenerative parameters. The agreement between the ratings of all raters were evaluated using a two-way random model of intra-class correlation coefficients (ICC).

resultsA total of 93 hospitalized patients were included in this study, with a mean age of 50.34 ± 15.95 years, yielding a total of 744 UVJs (C3-C7) for analysis. The CUBD system demonstrated high internal consistency (κ = 0.83 > 0.80, ICC = 0.92, 95% CI: 0.923–0.933). At individual cervical spinal levels, the CUBD classification demonstrates statistically significant correlations with patient age, disc height, DHI, and JH, while showing no significant association with patient gender. Moreover, we observed a progressive decrease in the uncinate process angle with advancing degeneration and an exacerbation of local kyphosis, particularly at the C6/7 level.

conclusionThe disc height-based CUBD classification system for UVJs degeneration demonstrates robust interobserver reliability. This innovative grading framework not only establishes a novel conceptual paradigm for current UVJs degeneration research but also exhibits statistically significant correlations with global cervical degenerative changes, indicating substantial clinical applicability.

Indexed as

Cervical VertebraeIntervertebral DiscIntervertebral Disc DegenerationAdultAgedFemaleHumansMaleMiddle AgedReproducibility of ResultsTomography, X-Ray ComputedCervical spondylosisCUBD classificationDegeneration stagingDegenerative parameter correlationInterobserver reliabilityUncovertebral joints degeneration

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.