Visualising viral interactions and mechanisms at the nanoscale with expansion microscopy.

Lisa Övermöhle, Maximilian Baum, Rohan Bhatia, Karin Byskata, Katharina M Scherer

Abstract readReview

In one paragraph

Review in Npj viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Tunneling nanotubes contribute to Zika virus pathogenesis at the maternal-fetal interfacemBio · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lisa Övermöhle *Institute of Microbiology and Biotechnology, University of Bonn, Bonn, Germany.

Maximilian Baum *Institute of Microbiology and Biotechnology, University of Bonn, Bonn, Germany.

Rohan BhatiaClausius-Institute of Physical and Theoretical Chemistry, University of Bonn, Bonn, Germany.

Karin ByskataInstitute of Microbiology and Biotechnology, University of Bonn, Bonn, Germany.

Katharina M SchererInstitute of Microbiology and Biotechnology, University of Bonn, Bonn, Germany. k.scherer@uni-bonn.de.

Funding

Horizon 2020 Framework Programme 101035817Ministry of Culture and Science of the State of North Rhine-Westphalia, Germany NRW Returning Scholars Programme

6 · The paper itself

Abstract

Expansion microscopy is a groundbreaking technique that enables nanoscale imaging of biological specimens using standard optical microscopes. By embedding specimens in swellable hydrogels, it achieves sub-diffraction resolution. Compatible with various tissue types, it offers 3D, multi-colour visualisation of cellular and sub-cellular structures. While challenges remain, like sample isotropy and preservation of molecular integrity, expansion microscopy is a transformative tool for cell and neurobiology. Here, we discuss its potential for virology.

Identifiers

PMID41495187

DOI10.1038/s44298-025-00169-y

PMCPMC12775147

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.