Evidence map›Paper›PMID 41495157›Full record

Trial reportScientific reports2026

Allogeneic acellular dermal matrix versus connective tissue graft for multiple RT2 gingival recessions: a randomized controlled trial.

Jie Yang, Zixuan Fan, Ting Hao, Jianping Xiao, Yanfen Li, Weibin Sun, Baochun Tan

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jie YangDepartment of Periodontology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, 210008, P.R. China.
Zixuan FanDepartment of Periodontology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, 210008, P.R. China.
Ting HaoDepartment of Periodontology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, 210008, P.R. China.
Jianping XiaoDepartment of Periodontology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, 210008, P.R. China.
Yanfen LiDepartment of Periodontology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, 210008, P.R. China. liyanfen2003@126.com.
Weibin SunDepartment of Periodontology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, 210008, P.R. China. wbsun@nju.edu.cn.
Baochun TanDepartment of Periodontology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, 210008, P.R. China. tanbaochun2002@163.com.

Funding

"2015" Cultivation Program for Reserve Talents for Academic Leaders of Nanjing Stomatological School, Medical School of Nanjing University 0223A202High-Level Hospital Construction Project of Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University 0224C024High-Level Hospital Construction Project of Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University 0224C045Jiangsu Provincial Medical Key Discipline (Laboratory) Cultivation Unit JSDW202246Medical Science and Technology Development Foundation, Nanjing Department of Health YKK23180the National Key R&D of Program of China 2022YFC2504200
6 · The paper itself

Abstract

Acellular dermal matrix (ADM) is an alternative to autologous tissue grafts that are commonly utilized in soft tissue augmentation procedures. This randomized clinical trial evaluated the clinical effectiveness of allogeneic ADM versus connective tissue graft (CTG) in treating multiple recession type (RT) 2 gingival recessions using a modified tunnel technique. A total of 40 patients were randomly assigned to either the CTG group (n=20) or the ADM group (n=20). Clinical parameters, including the plaque index (PI), gingival index (GI), probing depth (PD), clinical attachment level (CAL), keratinized tissue width (KTW), recession depth (RD), and gingival thickness (GT), were assessed at baseline and 12 months. Both groups showed significant improvements in CAL, KTW, RD, and GT at 12 months compared to baseline. No significant differences in PI, GI, PD, mean root coverage (MRC), complete root coverage (CRC) or the Root Coverage Esthetic Score (RES) were observed between the CTG and ADM groups. The CTG group demonstrated greater gains in GT and KTW (p<0.05), whereas the ADM group reported significantly lower postoperative pain (p<0.05). ADM and CTG yielded comparable root coverage and aesthetics. CTG provided superior tissue augmentation, whereas ADM offered better patient comfort. In conclusion, allogeneic ADM is a promising alternative for the treatment of RT2 gingival recessions.

Indexed as

Acellular DermisConnective TissueGingival RecessionAdultFemaleGingivaHumansMaleTransplantation, HomologousTreatment OutcomeAcellular dermal matrixAllogeneicConnective tissue graftModified tunnel techniqueRT2 gingival recessions

Identifiers

PMID41495157
PMCPMC12855969

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.