Evidence map›Paper›PMID 41495089›Full record

ReviewNPJ systems biology and applications2026

Rethinking medical education through systems biology to address complexity.

Laurent David, Pierre-Antoine Gourraud, Guillaume Lamirault, Patricia Lemarchand

Erratum issuedAbstract readReview
In one paragraph

Review in NPJ systems biology and applications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The End of Silo Medicine: A Case for Disease-Centered Subspecialization.Journal of evaluation in clinical practice · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Laurent DavidNantes Université, CHU Nantes, Inserm, CR2TI, Nantes, France. laurent.david@univ-nantes.fr.
Pierre-Antoine GourraudNantes Université, CHU Nantes, Inserm, CR2TI, Nantes, France.
Guillaume LamiraultNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France.
Patricia LemarchandNantes Université, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While reductionism has advanced biology and medicine, it fosters a fragmented understanding of health, ill-suited to modern challenges like chronic and systemic diseases. Systems biology offers a new perspective, framing biological entities within interconnected networks. Using French medical education as an example, we argue that systems thinking should be foundational, not optional. Integrating systems biology early in medical education can better prepare future physicians for biomedical complexity and precision medicine.

Indexed as

Education, MedicalSystems BiologyFranceHumansPrecision Medicine

Identifiers

PMID41495089
PMCPMC12820397

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.