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ArticleEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2026

Long-Term Outcome After the En Bloc Rotation of the Outflow Tracts Including Patients With Congenitally Corrected Transposition of the Great Arteries.

Michaela Kreuzer, Eva Sames-Dolzer, Andreas Tulzer, Roland Mair, Gregor Gierlinger, Fabian Seeber, Matija Bakos, Rudolf Mair

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Article in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Michaela KreuzerDivision of Pediatric and Congenital Heart Surgery, Kepler University Hospital, Linz 4020, Austria.ORCID 0000-0002-7499-7646
Eva Sames-DolzerDivision of Pediatric and Congenital Heart Surgery, Kepler University Hospital, Linz 4020, Austria.
Andreas TulzerMedical Faculty, Johannes Kepler University Linz, Linz 4040, Austria.
Roland MairDivision of Pediatric and Congenital Heart Surgery, Kepler University Hospital, Linz 4020, Austria.
Gregor GierlingerDivision of Pediatric and Congenital Heart Surgery, Kepler University Hospital, Linz 4020, Austria.ORCID 0000-0002-6358-5048
Fabian SeeberDivision of Pediatric and Congenital Heart Surgery, Kepler University Hospital, Linz 4020, Austria.
Matija BakosDepartment of Pediatrics, University Hospital Centre Zagreb, Zagreb 10000, Croatia.
Rudolf MairDivision of Pediatric and Congenital Heart Surgery, Kepler University Hospital, Linz 4020, Austria.ORCID 0000-0003-0935-1766

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDespite the increasing use of the en bloc rotation of the outflow tracts to treat patients with transposition of the great arteries with left ventricular outflow tract obstruction, long-term outcome data are scarce. Cases with simultaneous Mustard operation are a challenging technical expansion. This retrospective study aims to evaluate long-term outcomes in a single-centre cohort.

methodsAll patients undergoing the en bloc rotation at the Children's Heart Center Linz between 2003 and 2024 were retrospectively analysed.

resultsThe en bloc rotation was performed in 38 patients. Median age at operation was 4.1 (0.7; 23.9) months, weight 5.4 (3.7; 9.6) kg. A congenitally corrected transposition was present in 3 patients, in which a simultaneous Mustard procedure was performed. Median cardiopulmonary bypass time was 291 (270; 353) minutes, aortic cross-clamp time 160 (142; 185) minutes. The pulmonary valve could be preserved in 24 children (63%). Two patients died during the hospital stay (5%). During a follow-up period of median 9.3 (4.4; 14.3) years, 3 further children deceased, 5 surgical reinterventions were necessary. There was no death or surgical reintervention in the congenitally corrected transposition group.

conclusionsThe long-term outcome of the en bloc rotation is very promising, as could be expected due to the anatomic repair with growth potential in all tubular structures. The increased experience also with the Mustard operation allowed the combination of both complex procedures with excellent short-term outcome. CLINICAL REGISTRATION NUMBER: EK Nr 1011/2025, Ethics committee of the Medical Faculty at the Johannes Kepler University Linz.

Indexed as

Arterial Switch OperationTransposition of Great VesselsVentricular Outflow ObstructionChildChild, PreschoolCongenitally Corrected Transposition of the Great ArteriesFemaleFollow-Up StudiesHumansInfantMaleRetrospective StudiesTreatment Outcomecomplex transpositionen bloc rotation of the outflow tractshalf-turned truncal switchtransposition of the great arteriestransposition with VSD and LVOTO

Identifiers

PMID41494983
PMCPMC12957926

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