Evidence map›Paper›PMID 41494908›Full record

Trial reportThorax2026

Online cognitive behaviour therapy for asthma-related anxiety: a randomised controlled trial.

Marianne Bonnert, Stephen Nash, Erik M Andersson, Sten Erik Erik Bergström, Jenny Görling, Christer Janson, Josefin Särnholm, Catarina Almqvist

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Thorax, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04230369 (Internet-delivered Cognitive Behaviour Therapy for Anxiety Related to Asthma), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04230369 naunknown statusnot on this map

Internet-delivered Cognitive Behaviour Therapy for Anxiety Related to Asthma: A Randomized Controlled Trial

TypeinterventionalSponsorKarolinska InstitutetRan2020 to 2025Enrolled90ConditionsAsthma, AnxietyArmsExposure-based Internet-CBT, Treatment as usual
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Research advances in non-pharmacological interventions in pediatric asthma].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marianne BonnertCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Stockholm County, Sweden marianne.bonnert@ki.se.ORCID http://orcid.org/0000-0002-0140-773X
Stephen NashDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm County, Sweden.ORCID http://orcid.org/0000-0003-2086-1740
Erik M AnderssonDivision of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Stockholm County, Sweden.ORCID http://orcid.org/0000-0003-0088-8719
Sten Erik Erik BergströmPediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Stockholm County, Sweden.ORCID http://orcid.org/0000-0003-2483-3296
Jenny GörlingCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Stockholm County, Sweden.ORCID http://orcid.org/0009-0001-6118-7732
Christer JansonDepartment of Medical Sciences: Respiratory Medicine, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0001-5093-6980
Josefin SärnholmDivision of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Stockholm County, Sweden.ORCID http://orcid.org/0000-0002-9872-4781
Catarina AlmqvistDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm County, Sweden.ORCID http://orcid.org/0000-0002-1045-1898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAnxiety affects up to one-third of adults with asthma and is linked to poorer disease outcomes and reduced quality of life. This study evaluated the efficacy of therapist-guided, internet-delivered cognitive behavioural therapy (ICBT) versus treatment as usual plus medical education for reducing asthma-related anxiety.

methodsA randomised controlled trial was conducted including 90 adult participants with anxiety related to asthma. ICBT was therapist-guided and lasted 8 weeks. The primary outcome, the Catastrophising about Asthma Scale, was assessed from pretreatment to the primary endpoint at 16 weeks. Secondary outcomes included asthma control, avoidance behaviour and quality of life. Forced expiratory volume in 1 s (FEV

resultsICBT demonstrated a significantly larger reduction in catastrophising about asthma than the control group (mean difference -18.53, 95% CI -25.54 to -11.53, p<0.001). Asthma control, avoidance behaviour, quality of life and other key outcomes improved significantly more in the ICBT group compared with controls. No changes in FEV

conclusionICBT effectively and safely reduces catastrophising about asthma, improves asthma control, avoidance behaviour and quality of life and represents a promising adjunct to routine medical care for patients with asthma complicated by anxiety. TRIAL REGISTRATION NUMBER: Clinicaltrials.gov (ID: NCT04230369).

Indexed as

AnxietyAsthmaCognitive Behavioral TherapyAdultFemaleForced Expiratory VolumeHumansInternetMaleMiddle AgedQuality of LifeTreatment OutcomeAsthmaComplementary MedicinePsychology

Identifiers

PMID41494908
PMCPMC13479204

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.