Evidence map›Paper›PMID 41494775›Full record

SynthesisThe British journal of general practice : the journal of the Royal College of General Practitioners2026

Why aren't they used? Systematic review of barriers to implementation of clinical decision support systems for early cancer detection in primary care.

Christina Derksen, Kate A Le Noury, Adriana B Akbar, Thomas Round, Fiona M Walter, Suzanne E Scott

Abstract readSystematic Review
In one paragraph

Synthesis in The British journal of general practice : the journal of the Royal College of General Practitioners, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christina DerksenWolfson Institute of Population Health, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK christina.derksen@qmul.ac.uk.ORCID 0000-0002-4663-1882
Kate A Le NouryBarts and the London School of Medicine and Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0009-0004-1136-7235
Adriana B AkbarBarts and the London School of Medicine and Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0009-0008-7852-5807
Thomas RoundSchool of Life Course and Population Sciences, King's College London, London, UK.ORCID 0000-0003-4382-1629
Fiona M WalterWolfson Institute of Population Health, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0000-0002-7191-6476
Suzanne E ScottWolfson Institute of Population Health, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0000-0001-5536-9612

Funding

Cancer Research UK EDDPGM-MAY22\100002
6 · The paper itself

Abstract

backgroundEarly cancer detection is crucial for patient outcomes. Clinical decision support systems (CDSSs) have been developed to assist with decision making about screening or symptomatic assessment in primary care, but implementation remains challenging.

aimTo compare barriers to implementation of cancer-specific CDSSs for screening and symptomatic presentation in primary care. DESIGN AND

settingSystematic mixed-methods literature review.

methodA subanalysis within a systematic review was conducted. Qualitative and quantitative data on barriers were coded into themes guided by the Theoretical Domains Framework. Frequencies of studies mentioning barriers were compared between CDSSs for cancer detection and other conditions, and between cancer-specific CDSSs for screening and symptomatic presentation.

resultsIn total, 29 cancer-specific CDSSs were identified, addressing screening (

conclusionThe function and healthcare context of CDSSs in the diagnostic process (symptomatic assessment or screening decision making) appears to be more relevant to implementation than the targeted condition. Involving stakeholders to clarify medicolegal issues and workflow integration is essential for the implementation of CDSSs for symptomatic presentation.

Indexed as

Decision Support Systems, ClinicalEarly Detection of CancerNeoplasmsPrimary Health CareHumansdecision support systems, clinicalearly detection of cancerimplementation scienceprimary health care

Identifiers

PMID41494775
PMCPMC13060716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.