Evidence map›Paper›PMID 41494731›Full record

SynthesisCell transplantation

Bioactive molecule delivery platforms in regenerative endodontic therapy: A systematic review and meta-analysis.

Kanwalpreet Kaur, Rayan Ibrahim H Binduhayyim, Ravinder S Saini, Shashit Shetty Bavabeedu, Sunil Kumar Vaddamanu, Anna Avetisyan, Artak Heboyan

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kanwalpreet KaurRutgers School of Dental Medicine, Newark, NJ, USA.
Rayan Ibrahim H BinduhayyimDepartment of Allied Dental Health Sciences, COAMS, King Khalid University, Abha, Saudi Arabia.
Ravinder S SainiDepartment of Allied Dental Health Sciences, COAMS, King Khalid University, Abha, Saudi Arabia.
Shashit Shetty BavabeeduDepartment of Restorative Dental Sciences, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Sunil Kumar VaddamanuDepartment of Allied Dental Health Sciences, COAMS, King Khalid University, Abha, Saudi Arabia.
Anna AvetisyanDepartment of Therapeutic Stomatology, Faculty of Stomatology, Yerevan State Medical University after Mkhitar Heratsi, Yerevan, Armenia.
Artak HeboyanDepartment of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.ORCID 0000-0001-8329-3205

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review examines emerging delivery systems for bioactive molecules within regenerative endodontic therapy (RET) where hydrogels, nanogels, and polymeric nanoparticles along with advanced nanocarriers such as liposomes aquasomes, vesosomes, and mesoporous silica nanoparticles form the primary focus. The extensive literature search in PubMed, Scopus, and Web of Science databases (until August 2025) yielded a total of 47 eligible articles, including

Indexed as

Drug Delivery SystemsRegenerative EndodonticsAnimalsDental PulpHumansNanoparticlescontrolled releasegrowth factorshydrogel scaffoldsnanocarriersnanoparticlespulp regenerationregenerative endodonticstissue engineering

Identifiers

PMID41494731
PMCPMC12775354

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.