Evidence map›Paper›PMID 41494146›Full record

Trial reportJournal of clinical oncology : official journal of the American Society of Clinical Oncology2026

Music Therapy Versus Cognitive Behavioral Therapy via Telehealth for Anxiety in Survivors of Cancer: A Randomized Clinical Trial.

Kevin T Liou, Joke Bradt, M Beatriz Currier, Raymond Baser, Katherine Panageas, Jodi MacLeod, Desiree Walker, Susan Q Li, Ana Maria Lopez, Kelly McConnell and 1 more

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kevin T LiouIntegrative Medicine Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-2438-9749
Joke BradtDepartment of Creative Arts Therapies, College of Nursing and Health Professions, Drexel University, Philadelphia, PA.
M Beatriz CurrierPsychosocial Oncology, Miami Cancer Institute, Miami, FL.
Raymond BaserDepartment of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
Katherine PanageasDepartment of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-6591-604X
Jodi MacLeodSociety for Integrative Oncology, Pepper Pike, OH.ORCID 0000-0002-3434-9011
Desiree WalkerYoung Survival Coalition, New York, NY.ORCID 0009-0004-4275-7252
Susan Q LiIntegrative Medicine Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Ana Maria LopezDepartment of Medical Oncology, Thomas Jefferson University, Philadelphia, PA.ORCID 0000-0002-2759-5353
Kelly McConnellDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY.
Jun J MaoIntegrative Medicine Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0001-9229-0380

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Acupuncture for Cognitive Health in Older Survivors of Prostate Cancer (ACHIEVE)K08CA266927 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Kevin T Liou · 2022 to 2026
$1.2M
NCI NIH HHS K08 CA266927NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeAnxiety is prevalent, disruptive, and undertreated among survivors of cancer. Cognitive behavioral therapy (CBT) is the first-line treatment, but not all individuals have access, respond to treatment, or prefer this option because of stigma. Music therapy is effective for short-term anxiety reduction, but it is unknown whether it is noninferior to first-line CBT for long-term anxiety reduction.

methodsThis comparative effectiveness trial randomly assigned English- or Spanish-speaking survivors of cancer to seven weekly telehealth sessions of music therapy or CBT. The coprimary end points were changes in the Hospital Anxiety and Depression Scale (HADS) anxiety score at weeks 8 and 26. The noninferiority margin was 0.35 standard deviations, informed by a minimal clinically important difference (MCID) of 1.7 points. Secondary outcomes included fatigue, depression, insomnia, pain, cognitive dysfunction, and health-related quality of life.

resultsAmong N = 300 patients, 74.7% was female, 76.5% was White, and 19.0% was Hispanic. At week 8, the mean change in HADS anxiety score was -3.12 (95% CI, -3.59 to -2.65) in music therapy and -2.97 (95% CI, -3.45 to -2.50) in CBT; the between-group difference was -0.15 (95% CI, -0.78 to 0.49), within the noninferiority margin of 1.20 (

conclusionMusic therapy is noninferior to CBT for anxiety in survivors of cancer. Both telehealth interventions produced clinically meaningful, durable improvements in anxiety.

Indexed as

AnxietyCancer SurvivorsCognitive Behavioral TherapyMusic TherapyNeoplasmsAdultAgedFemaleHumansMaleMiddle AgedQuality of LifeTelemedicineTreatment Outcome

Identifiers

PMID41494146
PMCPMC12879169

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.