ReviewOdontology2026
Beyond the biofilm: KLF2 as a molecular gatekeeper in periodontal health and disease.
Review in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodontal disease is a chronic inflammatory condition resulting from complex interactions between microbial dysbiosis and host immune responses, leading to progressive destruction of the periodontium. Kruppel-like factor 2 (KLF2), a zinc-finger transcription factor, has emerged as a key regulator of immune modulation and tissue homeostasis. KLF2 orchestrates anti-inflammatory pathways, controls immune cell activation, and influences periodontal tissue integrity. Dysregulation of KLF2 is implicated in enhanced inflammation and periodontal tissue breakdown. This review summarizes the molecular biology of KLF2, its role in immune regulation, and its emerging significance in periodontal health and disease. We also discuss potential therapeutic applications targeting KLF2 pathways for improved periodontal disease management.
Indexed as
Identifiers
41493724What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.