ReviewCurrent pain and headache reports2026
The Interictal State of Migraine: Understanding the Hidden Burden Between Attacks.
Review in Current pain and headache reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Psychological interventions for migraine.Nature reviews. Neurology · 2026Review
- Translation and validation of the Migraine Interictal Burden Scale (MIBS-4) in an Italian clinical cohort.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- The Relevance of Crystal Clear and Unclear Days to Evaluate Residual Interictal Burden in Patients With Migraine Treated With CGRP Monoclonal Antibodies.European journal of neurology · 2026Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewMigraine is a complex neurological disorder characterized by recurrent attacks superimposed on an underlying state of persistent susceptibility. The interictal state, which is the time between acute episodes, is associated with symptoms that affect cognitive, functional, psychological, interpersonal, and socioeconomic domains. The objectives of this review are to define the interictal state of migraine, distinguish trigger subtypes, and investigate the transition from the interictal state to a migraine attack. RECENT
findingsStudies using assessment tools such as the Migraine Interictal Burden Scale (MIBS-4) have documented severe interictal burden in a majority of patients in several large-scale studies; however, the interictal burden has traditionally received limited attention despite its substantial impact on patients. By highlighting gaps in current research and clinical management, this work underscores the need to address both ictal and interictal states, aiming to improve patient outcomes and enhance awareness of this underrecognized aspect of migraine.
Indexed as
Identifiers
41493688What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.