Evidence map›Paper›PMID 41493595›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Increasing tongue pressure with CAD/CAM palatal augmentation plate for tongue cancer patients with glossectomy.

Yi-Fang Huang, Chih-Hung Lin, Yu-Fang Liao, Wei-Han Chang

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Yi-Fang HuangDepartment of General Dentistry, Chang Gung Memorial Hospital, Linkou, 33305, Taiwan. yifang0324@gmail.com.
Chih-Hung LinCollege of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.
Yu-Fang LiaoCollege of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.
Wei-Han ChangDepartment of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Keelung, 20405, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis prospective study evaluated the impact of computer-aided design/manufacturing (CAD/CAM) palatal augmentation prostheses (PAPs) rehabilitation on maximum tongue pressure in tongue cancer patients underwent glossectomy.

methodsTwelve patients (7 men, 5 women; mean age 53.2 years) with T1N0M0 or T2N0M0 tongue cancer that had undergone a type IIIa glossectomy without radiotherapy or chemotherapy were enrolled. All the participants had intact palates for good retention of PAP. Six weeks postoperatively, maxillary arches were scanned with an intraoral scanner; PAPs were digitally designed to lower the palatal vault utilizing CAD and then were fabricated from biocompatible PMMA via 3D printing and delivered. Patients wore the PAP daily and performed tongue-PAP contact exercises for at least four hours per day over six months. Maximum tongue pressure was measured using the Iowa Oral Performance Instrument before PAP delivery and after six months of rehabilitation. Statistical analysis was conducted using ANOVA with p < 0.05 considered significant.

resultsMean maximum tongue pressure increased from 16.93 ± 13.16 kPa pre-rehabilitation to 26.93 ± 15.60 kPa post-rehabilitation (median: 11.9 to 21.9 kPa). ANOVA showed a significant improvement (F = 5.31, p = 0.0038).

conclusionCAD/CAM PAP rehabilitation significantly improved the maximum tongue pressure in glossectomy patients, suggesting potential benefits for oral-phase swallowing efficiency. Early postoperative delivery through a digital workflow minimized tongue-palate distance, enabling prompt exercises, and accelerating functional recovery. This approach represents an innovative rehabilitation strategy. Integration of pressure sensors into PAPs could enable real-time monitoring of tongue activity, expanding their role as dynamic training devices.

Indexed as

Computer-Aided DesignGlossectomyTongueTongue NeoplasmsAdultAgedFemaleHumansMaleMiddle AgedPalatePressurePrinting, Three-DimensionalProspective StudiesProsthesis DesignCAD/CAMGlossectomyPalatal augmentation prostheses (PAPs)Tongue cancerTongue pressure

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.