Evidence map›Paper›PMID 41493556›Full record

ReviewArchives of microbiology2026

Resurgence of human metapneumovirus: an overview of past and current trends.

Ruchi Pathak, Murtaza Vandeliwala, Paresh Patel, Nisarg Patel, Kaushika Patel

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruchi PathakDepartment of Pharmaceutical Chemistry, L. J. Institute of Pharmacy, L J University, Ahmedabad, 382 210, India.
Murtaza VandeliwalaDepartment of Pharmaceutical Chemistry, L. J. Institute of Pharmacy, L J University, Ahmedabad, 382 210, India.
Paresh PatelDepartment of Pharmaceutical Chemistry, L. J. Institute of Pharmacy, L J University, Ahmedabad, 382 210, India.
Nisarg PatelDepartment of Respiratory Medicine, GMERS Medical College, Himmatnagar, 383001, Gujarat, India.
Kaushika PatelDepartment of Pharmaceutical Technology, L. J. Institute of Pharmacy, L J University, Ahmedabad, 382 210, India. kaushikaspatel@gmail.com.ORCID http://orcid.org/0000-0002-5482-9063

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human metapneumovirus (HMPV) is a major respiratory pathogen belonging to the Pneumoviridae family that primarily affects children, the elderly, and immunocompromised individuals. Since its discovery in 2001, HMPV has been recognized as a significant cause of acute respiratory infections (ARIs) worldwide, exhibiting seasonal peaks and recurring outbreaks. In recent years, the virus has shown an unusual resurgence, particularly in the post-COVID-19 era, emphasizing the need for renewed clinical and epidemiological attention. This review provides a comprehensive overview of HMPV, encompassing its epidemiology, virion structure, replication mechanisms, host-pathogen interaction, clinical manifestations, diagnostic strategies, and current therapeutic approaches. Special attention is given to recent epidemiological trends, molecular insights derived from structural studies of viral proteins, and the challenges faced in developing vaccines and antiviral agents. Additionally, the review discusses the potential of plant-derived bioactive compounds as alternative or complementary therapeutic options. By consolidating the latest global data and highlighting existing knowledge gaps, the work aims to facilitate a better understanding of HMPV pathogenesis and guide future research directions for improved surveillance, diagnosis, and management of HMPV infections.

Indexed as

MetapneumovirusParamyxoviridae InfectionsRespiratory Tract InfectionsAntiviral AgentsHost-Pathogen InteractionsHumansAntiviral AgentsHuman metapneumovirus (HMPV)Plant-based antiviral therapyRespiratory infectionsVaccine developmentViral pathogenesis

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.