Evidence map›Paper›PMID 41493542›Full record

ArticleJMIR medical education2026

Comparing AI-Assisted Problem-Solving Ability With Internet Search Engine and e-Books in Medical Students With Variable Prior Subject Knowledge: Cross-Sectional Study.

Ajiith Xavier, Syed Shariq Naeem, Waseem Rizwi, Hiramani Rabha

Abstract readComparative Study
In one paragraph

Article in JMIR medical education, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ajiith Xavier *Department of Pharmacology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Medical Road, Aligarh, Uttar Pradesh, 202001, India, 91 9634912166.ORCID 0009-0000-4159-5635
Syed Shariq Naeem *Department of Pharmacology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Medical Road, Aligarh, Uttar Pradesh, 202001, India, 91 9634912166.ORCID 0000-0003-4460-4597
Waseem RizwiDepartment of Pharmacology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Medical Road, Aligarh, Uttar Pradesh, 202001, India, 91 9634912166.ORCID 0000-0003-0850-090X
Hiramani RabhaDepartment of Pharmacology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Medical Road, Aligarh, Uttar Pradesh, 202001, India, 91 9634912166.ORCID 0009-0003-1603-1995

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Artificial intelligence (AI), particularly large language models (LLMs) such as ChatGPT (OpenAI), is rapidly influencing medical education. Its effectiveness for students with varying levels of prior knowledge remains underexplored. Objective: This study aimed to evaluate the performance of medical students with and without formal pharmacology knowledge when using AI-LLM GPTs, internet search engines, e-books, or self-knowledge to solve multiple-choice questions (MCQs). Methods: A cross-sectional study was conducted at a tertiary care teaching hospital with 100 medical students, divided into a "naive" group (n=50; no pharmacology training) and a "learned" group (n=50; completed pharmacology training). The study was started after approval from the Institutional Ethics Committee of Jawaharlal Nehru Medical College Hospital, Aligarh Muslim University (1018/IEC/23/8/23). Each participant answered 4 sets of 20 MCQs using self-knowledge, e-books, Google, or ChatGPT-4o. Scores were compared using analysis of covariance with self-knowledge scores as a covariate. Results: Learned students significantly outperformed naive students across all methods (P<.001), with the largest effect size in the AI-LLM GPT set (partial η²=0.328). For both groups, the performance hierarchy was AI-LLM GPT > internet search engine > self-knowledge ≈ e-books. Notably, the naive students who used AI scored higher (mean 13.24, SD 3.31) than the learned students who used Google (mean 12.14, SD 2.01; P=.01) or e-books (mean 10.22, SD 3.12; P<.001). Conclusions: AI-LLM GPTs can significantly enhance problem-solving performance in MCQ-based assessments, particularly for students with limited prior knowledge, even allowing them to outperform knowledgeable peers using traditional digital resources. This underscores the potential of AI to transform learning support in medical education, although its impact on deep learning and critical thinking requires further investigation.

Indexed as

Artificial IntelligenceInternetPharmacologyProblem SolvingSearch EngineStudents, MedicalCross-Sectional StudiesEducational MeasurementEducation, Medical, UndergraduateFemaleHumansMaleYoung AdultAIartificial intelligenceChatGPTcognitive performancelarge language modelsLLMmedical educationsubject-naive learners

Identifiers

PMID41493542
PMCPMC12772426

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.