Evidence map›Paper›PMID 41493489›Full record

ReviewBreast cancer research and treatment2026

RISE UP for breast cancer 2024: conference highlights & takeaways.

Taylor Glatt, Katherine Leggat-Barr, Nandini Seth, Diane Heditsian, Laura van 't Veer, Lajos Pusztai, Elissa Price, Nola Hylton, Silvia Formenti, Hope Rugo and 15 more

Abstract readReview
In one paragraph

Review in Breast cancer research and treatment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Taylor GlattTufts University School of Medicine, Tufts University, Boston, MA, USA.
Katherine Leggat-BarrTufts University School of Medicine, Tufts University, Boston, MA, USA.
Nandini SethUniversity of California, 1825 4Th St, 3Rd Floor, San Francisco, CA, 94158, USA.
Diane HeditsianUniversity of California, 1825 4Th St, 3Rd Floor, San Francisco, CA, 94158, USA.
Laura van 't VeerUniversity of California, 1825 4Th St, 3Rd Floor, San Francisco, CA, 94158, USA.
Lajos PusztaiYale University Cancer Center, Yale University, New Haven, CT, USA.
Elissa PriceUniversity of California, 1825 4Th St, 3Rd Floor, San Francisco, CA, 94158, USA.
Nola HyltonUniversity of California, 1825 4Th St, 3Rd Floor, San Francisco, CA, 94158, USA.
Silvia FormentiWeill Cornell Medical College, New York, NY, USA.
Hope RugoCity of Hope Cancer Center, Duarte, CA, USA.
Laura FejermanUC Davis Comprehensive Cancer Center, University of California, Davis, Davis, CA, USA.
Adetunji T ToriolaDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Carol FabianMedical Center, University of Kansas, Kansas City, KS, USA.
Andrea De CensiDivision of Medical Oncology, Department of Medicine, E.O. Ospedali Galliera, Genoa, Italy.
Daniel GrossmanUniversity of California, 1825 4Th St, 3Rd Floor, San Francisco, CA, 94158, USA.
Olufunmilayo OlopadeCenter for Clinical Cancer Genetics and Global Health, The University of Chicago, Chicago, IL, USA.
Andrea JacksonUniversity of California, 1825 4Th St, 3Rd Floor, San Francisco, CA, 94158, USA.
Sara HortonAccess and Diversity, Quantum Leap Healthcare Collaborative, San Francisco, CA, USA.
Kim RhoadsUniversity of California, 1825 4Th St, 3Rd Floor, San Francisco, CA, 94158, USA.
Carol LangeMasonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
Virginia BorgesDivision of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Elizabeth GarnerAmerican Medical Women's Association, Lexington, KY, USA.
Judy GarberDana-Farber Cancer Institute, Boston, MA, USA.
Douglas YeeMasonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
Laura EssermanUniversity of California, 1825 4Th St, 3Rd Floor, San Francisco, CA, 94158, USA. laura.esserman@ucsf.edu.

Funding

RISE UP for Breast CancerR13CA294950 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ESSERMAN, LAURA J · 2024 to 2024
$7k
California Breast Cancer Research Program B30CS8521NCI NIH HHS R13 CA294950NIH HHS R13CA294950
6 · The paper itself

Abstract

RISE UP (Revolutionizing Investigations to StEp Up Prevention) for breast cancer brought together leading cancer specialists, women's health providers, basic and population scientists, regulators, politicians, industry leaders, patient advocates, and more from around the world to discuss and chart a radical rethinking of breast cancer prevention and risk reduction through a lens of hormonal management across a woman's life course. The presentations at RISE UP were organized to outline a path forward by leveraging what we know about breast cancer biology, early detection, treatment, and endocrine therapy toward a better and sustainable approach for breast cancer prevention. Important conference considerations were to expand our thinking about prevention by broadly considering how the hormonal environment during different life phases or common benign conditions could be better managed to minimize breast cancer risk. This set the stage for transitioning to advances in risk prediction, promising risk-reducing agents, and biomarker-driven trials to test them. Biomarker-based trials discussed focused on 1) lower or intermittent doses of standard prevention agents, 2) drugs already approved for other health purposes, and 3) maximizing benefits from lifestyle interventions alone or in combination. Throughout RISE UP, there was a strong focus on promoting health equity, including comprehensive reproductive health access, equitable representation in clinical trials, and strategies to educate women, providers, and advocates about disparities in care and how to successfully reduce them. The meeting concluded with a competition for innovative approaches to breast cancer prevention that could be integrated into hormonal and women's health interventions. RISE UP was an innovative conference that provided a forum for cross-cutting topics in women's health that do not currently exist. The insights shared at RISE UP will be paradigm shifting in breast cancer prevention and women's health space in the years to come.

Indexed as

Breast NeoplasmsCongresses as TopicEarly Detection of CancerFemaleHumans

Identifiers

PMID41493489
PMCPMC12774930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.