Evidence map›Paper›PMID 41493421›Full record

ArticleThe international journal of medical robotics + computer assisted surgery : MRCAS2026

Development of a Flexible Parallel Wire Robot for Epicardial Interventions.

Aman Ladak, Johannes O Bonatti, Roger J Hajjar, Alaaeldin A Shalaby, Cameron N Riviere

Abstract read
In one paragraph

Article in The international journal of medical robotics + computer assisted surgery : MRCAS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Development of a Flexible Parallel Wire Robot for Epicardial Interventions.The international journal of medical robotics + computer assisted surgery : MRCAS · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aman LadakDepartment of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.
Johannes O BonattiDepartment of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Roger J HajjarGene and Cell Therapy Institute, Mass General Brigham, Boston, Massachusetts, USA.
Alaaeldin A ShalabyDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-2000-7678
Cameron N RiviereThe Robotics Institute, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.

Funding

Minimally Invasive Targeted Injection of Thermoresponsive Hydrogels for CardiomyopathyR01HL174945 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WILLIAM R WAGNER · 2025 to 2026
$1.4M
Carnegie Mellon University's GSA/Provost GuSH GrantNHLBI NIH HHS R01 HL174945NHLBI NIH HHS R01HL174945
6 · The paper itself

Abstract

backgroundHeartPrinter is a flexible parallel wire robot that adheres to the beating heart with vacuum suction at three bases. An injector head actuated by cables delivers gene therapy injections within the bounds of the bases. To deploy onto the epicardium, an introducer mechanism is required. On the heart, the robot's workspace and anatomical model registration to its pose are needed.

methodsWe present HeartPrinter's components and introducer mechanism, and assess them on an artificial beating heart. We evaluate accuracy for position determination of the bases and registering a three-dimensional heart scan.

resultsThe introducer mechanism successfully positioned HeartPrinter, and the bases adhered to the beating heart. The base positions and registration were calculated accurately with errors under 4 and 2 mm.

conclusionsThe introducer mechanism can deploy HeartPrinter on the epicardium, and HeartPrinter's components can operate on the heart. Workspace determination and registration demonstrate feasibility as preliminary concepts.

Indexed as

Cardiac Surgical ProceduresPericardiumRoboticsRobotic Surgical ProceduresEquipment DesignHeartHumansImaging, Three-Dimensionalbeating‐heart surgerycable‐driven parallel robotsepicardial interventiongene therapyrobotic surgerysubxiphoid access

Identifiers

PMID41493421
PMCPMC12772424

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.