Evidence map›Paper›PMID 41492977›Full record

ReviewEnvironmental science & technology2026

Oxidative Potential of Atmospheric Particulate Matter: A Review of the Role of Metal-Organic Interactions, Mechanistic Insights, and Key Determinants.

Manfei Lin, Jian Zhen Yu

Abstract readReview
In one paragraph

Review in Environmental science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Manfei LinJiangsu Provincial Key Laboratory of Environmental Engineering, Jiangsu Provincial Academy of Environmental Science, Nanjing 210036, China.ORCID 0009-0000-5378-3529
Jian Zhen YuDepartment of Chemistry and Division of Environment, Hong Kong University of Science & Technology, Clear Water Bay, Kowloon 999077, Hong Kong, China.ORCID 0000-0002-6165-6500

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress, resulting from antioxidant depletion or excessive reactive oxygen species (ROS) production, is a key mechanism linking ambient particulate matter (PM) exposure to adverse health effects. The oxidative potential (OP) of PM, a measure of inhaled PM's capacity to deplete antioxidants or generate ROS, is largely driven by transition metals (TMs) such as iron and copper. However, coexisting organic matter also modulates OP, both directly through its own redox activity and indirectly via interactions with TMs that alter redox cycling. This review synthesizes current understanding of TM-organic interactions and their influence on the OP of PM, as assessed by acellular assays. We discuss mechanistic insights, key determinants, and the complexity of these interactions. The importance of considering TM-organic interactions in evaluating aggregate OP from individual components and apportioning OP to specific chemical species is highlighted, with implications for mechanistic studies and health risk assessment.

Indexed as

MetalsParticulate MatterAir PollutantsAtmosphereOxidation-ReductionOxidative StressReactive Oxygen SpeciesAir PollutantsMetalsParticulate MatterReactive Oxygen Speciesacellular assayshealth effects of particulate mattermetal−organic interactionsoxidative potentialparticulate matterreactive oxygen species

Identifiers

PMID41492977
PMCPMC12825168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.