ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
[Comparison of the efficacy of trabeculectomy combined with Schlemm canal incision versus trabeculectomy alone in the treatment of primary open angle glaucoma].
Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesGlaucoma is the leading cause of irreversible blindness worldwide, with primary open-angle glaucoma (POAG) being the most common type. Trabeculectomy is currently the primary surgical treatment for POAG; however, its long-term efficacy remains suboptimal. This study aims to compare the therapeutic efficacy and safety of trabeculectomy combined with Schlemm canal incision (TCSCI) with trabeculectomy alone in order to provide new insights for POAG management.
methodsIn this retrospective case-control study, 47 patients (47 eyes) diagnosed with POAG at the Ophthalmology Center of Xiangya Hospital between May 2019 and May 2023 were included. Patients undergoing combined trabeculectomy and Schlemm canal incision were assigned to the TCSCI group, whereas those undergoing trabeculectomy alone were assigned to the trabeculectomy group. Postoperative assessments or follow-up were conducted on postoperative day 1 and at 1 week, 1 month, 2 months, 3 months, 6 months, 1 year, and 2 years. Best-corrected visual acuity, intraocular pressure (IOP), number of glaucoma medications, surgical success rate, and intraoperative and postoperative complications were compared between groups.
resultsNo significant difference was found in baseline data between the TCSCI group and trabeculectomy group (all
conclusionsBoth TCSCI and trabeculectomy effectively lower IOP and reduce the need for postoperative IOP-lowering medications in POAG patients. Compared with trabeculectomy alone, TCSCI offers a dual outflow pathway through Schlemm canal and external filtration, representing a safe and effective surgical option for POAG.
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