Evidence map›Paper›PMID 41492605›Full record

ReviewCureus2025

Distal Femoral Replacement Versus Open Reduction and Internal Fixation in Elderly Distal Femur Fractures: A Systematic Review and Meta-Analysis.

Ahmed Elnewishy, Mohamed Elgamal, Ahmed Elkohail, Mahmoud Noureldin, Ahmed Hamada, Pir Zarak Khan, Hagar Teama, Symeon Naoum

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ahmed ElnewishyTrauma and Orthopaedics, Royal Berkshire NHS Foundation Trust, Reading, GBR.
Mohamed ElgamalTrauma and Orthopaedics, Southend University Hospital, Southend-on-Sea, GBR.
Ahmed ElkohailTrauma and Orthopaedics, Princess Royal University Hospital, King's College Hospital NHS Foundation Trust, Orpington, GBR.
Mahmoud NoureldinTrauma and Orthopaedics, University Hospitals Sussex NHS Foundation Trust, Brighton, GBR.
Ahmed HamadaTrauma and Orthopedic, Royal Devon and Exeter Hospital, Exeter, GBR.
Pir Zarak KhanTrauma and Orthopaedics, Maidstone and Tunbridge Wells NHS Trust, Royal Tunbridge Wells, GBR.
Hagar TeamaPharmacy, Kafr El-Sheikh University Hospital, Kafr El-Shaikh, EGY.
Symeon NaoumTrauma and Orthopaedic Surgery, Royal Berkshire NHS Foundation Trust, Reading, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Distal femur fractures are a major cause of morbidity and mortality among older adults, often complicated by osteoporosis and comorbidities that hinder recovery. This systematic review and meta-analysis compared distal femoral replacement (DFR) and open reduction internal fixation (ORIF) for such fractures in elderly patients. A comprehensive search of PubMed, Scopus, Google Scholar, and the Cochrane Library identified six comparative studies including 688 patients. Pooled data showed a trend toward fewer reoperations with DFR (odds ratio (OR): 0.44, 95% confidence interval (CI): 0.16-1.21) and similar complication rates between DFR and ORIF (OR: 0.96, 95% CI: 0.37-2.54). Mortality was significantly lower in patients treated with DFR (OR: 0.32, 95% CI: 0.12-0.84). These findings suggest that DFR may reduce mortality and the need for revision surgery without increasing complications, supporting its consideration as an alternative option for elderly patients with distal femur fractures.

Indexed as

distal femoral replacement (dfr)distal femur fractureelderly traumaintraarticular distal femur fracturemorbidity and mortalityopen reduction internal fixation

Identifiers

PMID41492605
PMCPMC12765530

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.