Evidence map›Paper›PMID 41492584›Full record

ArticleCureus2025

Comparative Assessment of Color Stability in Four Commercial Clear Aligner Materials Exposed to Common Beverages: An In Vitro Study.

Sameer Narkhede, Paritosh Rao, Veera Sawant, Shreedaay Kambli, Nikita Garg, Shreyas P Shah, Sanpreet S Sachdev

Registry-linked trialAbstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07628491 (Colorimetric Stability of Finishing Clear Aligners According to Marginal Termination Design), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07628491 nacompletednot on this mapstarted 2026, after this paper: background citation

Colorimetric Stability of Finishing Clear Aligners According to Marginal Termination Design (Supragingival Versus Juxtagingival) After 14 Days of Intraoral Wear During Orthodontic Treatment: A Prospective Split-Mouth Study

TypeinterventionalSponsorGeorge Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu MuresRan2026 to 2026Enrolled50ConditionsMalocclusion, Esthetics, DentalArmsTri-layer thermoplastic finishing clear aligner
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sameer NarkhedeOrthodontics and Dentofacial Orthopedics, DY Patil University School of Dentistry, Navi Mumbai, IND.
Paritosh RaoOrthodontics and Dentofacial Orthopedics, DY Patil University School of Dentistry, Navi Mumbai, IND.
Veera SawantOrthodontics and Dentofacial Orthopedics, DY Patil University School of Dentistry, Navi Mumbai, IND.
Shreedaay KambliOrthodontics, Arte Aligners, Mumbai, IND.
Nikita GargOrthodontics, Dr. S.S. Tantia Dental College, Hospital and Research Center, Sri Ganganagar, IND.
Shreyas P ShahOral Medicine and Radiology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND.
Sanpreet S SachdevOral Pathology and Microbiology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Clear aligner therapy (CAT) has become a popular esthetic alternative to fixed orthodontic appliances, driven by advances in polymer science and digital manufacturing. However, staining and color instability remain significant clinical concerns, especially given patient non-compliance with recommended beverage restrictions. Limited comparative evidence exists regarding how different aligner polymers respond to common chromogenic beverages. Aim To evaluate and compare the color stability of four commercially available clear aligner materials, Invisalign® (polyurethane; Align Technology Inc., Tempe, Arizona, United States), ClearCorrect™ (polyethylene terephthalate glycol (PETG); Round Rock, Texas, United States), Illusion® (multilayer polyester blend; Laxmi Dental Ltd., Mumbai, India), and Graphy TC-85® (photocurable oligomer; Graphy Inc., Geumcheon-gu, Seoul, South Korea), following immersion in tea, coffee, cola, and red wine over a two-week period. Materials and methods This laboratory-based in vitro study used 40 aligner specimens (10 per brand), sectioned into standardized 10×10 mm samples. Specimens were randomly assigned to five immersion media (tea, coffee, cola, red wine, and distilled water). Color measurements (L*, a*, b*) were recorded at baseline, 24 hours, seven days, and 14 days using a VITA Easyshade® V (VITA Zahnfabrik H. Rauter GmbH & Co. KG, Germany) spectrophotometer. Total color change (ΔE) was calculated using the CIELAB formula. Data were analyzed using repeated-measures ANOVA with Tukey's post hoc tests (α=0.05). Results All aligners exhibited clinically acceptable baseline ΔE values (<3.3). Coffee and cola produced the highest discoloration across most materials. ClearCorrect™ and Illusion® demonstrated the greatest susceptibility, exceeding perceptible thresholds within 24 hours. Invisalign® showed moderate, beverage-independent staining, while Graphy TC-85® remained stable against acidic beverages but showed delayed tea-related discoloration. Time and beverage type significantly influenced ΔE values (p<0.001). Conclusion Color stability of clear aligners is strongly governed by polymer chemistry and beverage characteristics. PETG and multilayer polyester blends stain rapidly, polyurethane discolors moderately, and photocurable oligomers display beverage-specific behavior. Material-specific guidance and reinforced patient instructions are essential to maintain esthetic longevity of aligners.

Indexed as

clear alignercolour stabilitypetgpolyurethanespectrophotometry

Identifiers

PMID41492584
PMCPMC12764434

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.