Evidence map›Paper›PMID 41492581›Full record

ArticleCureus2025

Role of Rate of Force Development in Mediating the Relationship Between Task-Specific Fear and Chronic Low Back Pain Among Japanese Caregivers: A Pilot Cross-Sectional Mediation Study.

Teppei Abiko, Shin Murata, Hayato Shigetoh, Norihisa Matsumoto, Yamaguchi Hideaki, Michie Ohyama, Eiji Sakata, Wayne Hing

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Teppei AbikoDepartment of Physical Therapy, Faculty of Health Sciences, Kyoto Tachibana University, Kyoto, JPN.
Shin MurataDepartment of Physical Therapy, Faculty of Health Sciences, Kyoto Tachibana University, Kyoto, JPN.
Hayato ShigetohDepartment of Physical Therapy, Faculty of Health Sciences, Kyoto Tachibana University, Kyoto, JPN.
Norihisa MatsumotoFaculty of Rehabilitation, Reiwa Health Sciences University, Fukuoka, JPN.
Yamaguchi HideakiResearch Consultancy, Kyoto Tachibana University, Nagoya, JPN.
Michie OhyamaWelfare Equipment, NPO (Non-Profit Organization) Fukushiyogunet, Fukuoka, JPN.
Eiji SakataWelfare Equipment, NPO (Non-Profit Organization) Fukushiyogunet, Fukuoka, JPN.
Wayne HingFaculty of Health Sciences and Medicine, Bond University, Gold Coast, AUS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Chronic low back pain (CLBP) is prevalent among caregivers; however, the mechanisms linking psychological factors like fear of movement to pain are unclear. This study investigated whether the rate of force development (RFD), a measure of explosive strength, mediates the relationship between task-specific fear and CLBP intensity in this high-risk population. Methods Thirty-two Japanese care workers (13 CLBP, 19 healthy) performed sit-to-stand and stand-to-sit tasks on a force plate after rating their task-specific fear. Vertical ground reaction force was used to calculate early-phase RFD (0-100 ms) during stand-to-sit, the prespecified mediator. CLBP was defined as pain persisting for >3 months. Associations were analyzed using Spearman's correlation and a 1,000-sample bootstrap mediation model. Results Early-phase RFD (0-100 ms) during stand-to-sit correlated negatively with both task-specific fear (ρ = -0.43) and CLBP intensity (ρ = -0.51). The mediation analysis confirmed a significant indirect effect of fear on CLBP through RFD (B = 0.39, 95% CI (0.06, 1.30)). The total effect of fear on pain was also significant (B = 5.58, 95% CI (0.39, 18.61)). Conclusion In caregivers, higher task-specific fear is associated with suppressed RFD during the stand-to-sit task, reflecting a force-control deficit linked to CLBP. Early-phase RFD is a promising biomarker for identifying fear-driven motor inhibition. These findings suggest that workplace interventions that combine graded exposure with explosive-strength training may effectively reduce the risk of chronic pain.

Indexed as

chronic low back painkinesiophobiamediation analysisrate of force developmentsit-to-stand

Identifiers

PMID41492581
PMCPMC12765356

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.