Evidence map›Paper›PMID 41492459›Full record

ArticleJournal of pharmaceutical analysis2025

A customizable continuous and near real-time TEER platform to study anti-cancer drug toxicity in barrier tissues.

Curtis G Jones, Chengpeng Chen

Abstract read
In one paragraph

Article in Journal of pharmaceutical analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Curtis G JonesDepartment of Chemistry and Biochemistry, University of Maryland, Baltimore County, Baltimore, MD, 21250, USA.
Chengpeng ChenDepartment of Chemistry and Biochemistry, University of Maryland, Baltimore County, Baltimore, MD, 21250, USA.

Funding

A physiological and translational liver model to study the metabolism-modulating roles of extracellular matrix microstructuresR35GM146779 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI Chengpeng Chen · 2022 to 2026
$1.7M
NIGMS NIH HHS R35 GM146779
6 · The paper itself

Abstract

Barrier tissues such as the endothelium are critical in the regulation of mass transfer throughout the body. Trans-endothelium/epithelium electrical resistance (TEER) is an important bioelectrical measurement technique to monitor barrier integrity. Although available on the market, TEER sensors are usually expensive and bulky and do not allow customization around experimental setups like specific microfluidic settings. We recently reported a customizable TEER sensor built on Arduino. In this paper, we significantly advanced a new generation of TEER sensors characterized by 1) a large dynamic range of 242-11,880 Ω·cm

Indexed as

Barrier tissuesCardiotoxicityDoxorubicinEndotheliumSensorTEER

Identifiers

PMID41492459
PMCPMC12765242

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.