Evidence map›Paper›PMID 41492455›Full record

ArticleJournal of pharmaceutical analysis2025

Reactivating T cell immunity in Wnt-hyperactivated non-small cell lung cancer through a supramolecular droplet of carnosic acid and peptide.

Na Liu, Yuzhen Tu, Hanyu Wang, Xiaoqiang Zheng, Fanpu Ji, Mingsha Geng, Xin Wei, Jingman Xin, Wangxiao He, Qian Zhao and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmaceutical analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Na LiuDepartment of Infectious Diseases and Hepatology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, China.
Yuzhen TuDepartment of Clinical Laboratory, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, 361000, China.
Hanyu WangFaculty of Arts and Science, University of Toronto, Toronto, Ontario, M5S 1A1, Canada.
Xiaoqiang ZhengInstitute for Stem Cell & Regenerative Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, China.
Fanpu JiDepartment of Infectious Diseases and Hepatology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, China.
Mingsha GengDepartment of Network Information, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, China.
Xin WeiDepartment of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Jingman XinSchool of Stomatology, Xi'an Jiaotong University, Xi'an, 710049, China.
Wangxiao HeDepartment of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Qian ZhaoDepartment of Otorhinolaryngology Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Tianya LiuDepartment of Infectious Diseases and Hepatology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Wnt/β-catenin signaling pathway is renowned for its contribution to the immunosuppressive microenvironment in non-small cell lung cancer (NSCLC). Consequently, inhibiting this pathway has emerged as a promising strategy to enhance immune activation and reinstate T cell responses in cancer treatment. In this study, we initially investigate the metabolic characteristics of Wnt-hyperactivated NSCLC using mass spectroscopic detection in a mouse

Indexed as

Cancer therapyImmunotherapyNon-small cell lung cancerTumor microenvironmentWnt/β-catenin signal

Identifiers

PMID41492455
PMCPMC12765257

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.