ArticleAmerican heart journal plus : cardiology research and practice2026
Predictive value of abnormal coronary computed tomography angiography in patients with Normal single-photon emission computed tomography scan.
Article in American heart journal plus : cardiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The aim of this study was to assess the prognostic value of abnormal coronary computed tomography angiography (CCTA) in patients with normal single-photon emission computed tomography (SPECT) study. Methods: We retrospectively enrolled patients with normal SPECT scans and abnormal CCTA studies, who were categorized according to CCTA findings into obstructive with ≥50 %, and non-obstructive CAD <50 % coronary artery stenosis. Major adverse cardiac events (MACE) was defined as cardiovascular death and non-fatal myocardial infarction. Results: Among 1558 eligible patients, there were 1356 (87.1 %) patients with non-obstructive CAD and 202 (12.9 %) patients with obstructive CAD. Over a median follow-up of 10.4 ± 5.1 years, a total of 87 MACEs were reported. Patients with obstructive CAD were older (67.4 ± 8 vs. 60.3 ± 10 years, Conclusion: Obstructive CAD on CCTA is associated with significantly higher long-term risk of MACE in comparison to non-obstructive CAD in patients with normal SPECT.
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