Evidence map›Paper›PMID 41492432›Full record

ReviewPreventive nutrition and food science2025

Hypoglycemic and Antioxidant Activities of Exopolysaccharides Produced by Lactic Acid Bacteria: A Systematic Review.

Neny Mariyani, Lilis Nuraida, Hanifah Nuryani Lioe, Ratih Dewanti-Hariyadi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Preventive nutrition and food science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Neny MariyaniDepartment of Food Science and Technology, Faculty of Agricultural Engineering and Technology, IPB University (Bogor Agricultural University), IPB Dramaga Campus, Bogor 6680, Indonesia.ORCID https://orcid.org/0000-0002-1750-3566
Lilis NuraidaDepartment of Food Science and Technology, Faculty of Agricultural Engineering and Technology, IPB University (Bogor Agricultural University), IPB Dramaga Campus, Bogor 6680, Indonesia.ORCID https://orcid.org/0000-0002-0847-5786
Hanifah Nuryani LioeDepartment of Food Science and Technology, Faculty of Agricultural Engineering and Technology, IPB University (Bogor Agricultural University), IPB Dramaga Campus, Bogor 6680, Indonesia.ORCID https://orcid.org/0000-0003-1364-0798
Ratih Dewanti-HariyadiDepartment of Food Science and Technology, Faculty of Agricultural Engineering and Technology, IPB University (Bogor Agricultural University), IPB Dramaga Campus, Bogor 6680, Indonesia.ORCID https://orcid.org/0000-0002-3276-1627

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactic acid bacteria (LAB) are widely utilized in various fermented food products and possess a Generally Recognized as Safe status. LAB produce exopolysaccharides (EPS), which are one of the components of postbiotics. Studies on EPS from LAB have attracted considerable interest because of their potential biological functions and associated health benefits, including hypoglycemic and antioxidant functions. However, there is still a lack of reviews that summarize available studies regarding the relationship between EPS characteristics and hypoglycemic and antioxidant activities. Therefore, the present systematic review aimed to identify the characteristics of EPS that influence its hypoglycemic and antioxidant activities. This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Twenty-seven articles from Google Scholar, PubMed, and Scopus, which reported the sources of EPS-producing LAB, fermentation media, and conditions, as well as their EPS yields, molecular weights (MWs), and monosaccharide components, were selected based on the inclusion and exclusion criteria and whole literature screening. The MWs of EPS ranged from 10.75 to 9,549 kDa and from 2.4 to 9,549 kDa based on hypoglycemic and antioxidant activity assays, respectively. Generally, glucose and mannose were found in almost all EPS that were produced. This study indicated that MW and monosaccharide components influence hypoglycemic and antioxidant activities (

Indexed as

antioxidantsexopolysaccharideshypoglycemic agentslactic acid bacteria

Identifiers

PMID41492432
PMCPMC12765615

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.