ArticlePreventive nutrition and food science2025
Effects of Dietary Supplementation with Coriander Seed Powder on Serum Lipid Profile, Glycemic Indices, and Oxidative Stress Biomarkers in Patients with Type 2 Diabetes Mellitus: A Randomized, Double-Blind, Placebo-Controlled Trial.
Article in Preventive nutrition and food science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This study aimed to investigate the effects of coriander seed supplementation on serum lipid profiles, glycemic indices, and oxidative stress biomarkers in patients with type 2 diabetes mellitus (T2DM). In total, 40 such patients aged 30－60 years were allocated into two groups receiving either coriander seed powder (1,000 mg/d, n=20) or placebo (1,000 mg/d, n=20) for 6 weeks. Serum lipid profile: total cholesterol (TC), high-density lipoprotein cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglycerides (TGs); anthropometric measurements; dietary intake; and biochemical parameters including fasting blood serum (FBS), serum insulin, homeostatic model assessment for insulin resistance (HOMA-IR), and malondialdehyde (MDA); and total antioxidant capacity (TAC) were assessed before and after supplementation. Coriander seed powder markedly reduced the FBS (156.15±23.19 to 130.30±21.15 mg/dL), serum insulin (17.72±0.47 to 17.12±0.76 µU/mL), HOMA-IR (6.82±0.95 to 5.52±0.99), TC (183.85±55.68 to 145.20±31.36 mg/dL), TG (152.50±37.59 to 130.40±27.96 mg/dL), LDL-C (127.35±23.45 to 111.40±25.71 mg/dL), and MDA (1.65±0.15 to 1.49±0.15 nmol/mL). However, the serum TAC significantly increased (1.93±0.12 to 1.97±0.09 mmol/L) (
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