Evidence map›Paper›PMID 41492375›Full record

ArticleBioscience of microbiota, food and health2026

Epidemiological study on the effects of gut microbiota and nutrients on breath hydrogen and methane concentrations.

Satoshi Sato, Daisuke Chinda, Shigeyuki Nakaji, Masakazu Tobinai, Nao Ishidoya, Keisuke Furusawa, Kaede Miyashiro, Kenta Yoshida, Chikara Iino, Kaori Sawada and 2 more

Abstract read
In one paragraph

Article in Bioscience of microbiota, food and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Satoshi SatoDepartment of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki-shi, Aomori 036-8562, Japan.
Daisuke ChindaDivision of Endoscopy, Hirosaki University Hospital, 53 Honcho, Hirosaki-shi, Aomori 036-8563, Japan.
Shigeyuki NakajiDepartment of Preemptive Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki-shi, Aomori 036-8562, Japan.
Masakazu TobinaiDepartment of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki-shi, Aomori 036-8562, Japan.
Nao IshidoyaDepartment of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki-shi, Aomori 036-8562, Japan.
Keisuke FurusawaDepartment of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki-shi, Aomori 036-8562, Japan.
Kaede MiyashiroDepartment of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki-shi, Aomori 036-8562, Japan.
Kenta YoshidaDepartment of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki-shi, Aomori 036-8562, Japan.
Chikara IinoDepartment of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki-shi, Aomori 036-8562, Japan.
Kaori SawadaDepartment of Preemptive Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki-shi, Aomori 036-8562, Japan.
Tatsuya MikamiDepartment of Preemptive Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki-shi, Aomori 036-8562, Japan.
Hirotake SakurabaDepartment of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki-shi, Aomori 036-8562, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breath hydrogen concentration measurement is a valuable tool for assessing the intestinal environment; however, few epidemiological studies have investigated the relationship between exhaled hydrogen and gut microbiota in healthy subjects. This study aimed to epidemiologically elucidate the relationships between exhaled hydrogen, gut microbiota, and nutrient intake in healthy residents of the Iwaki area of Hirosaki City, Aomori Prefecture, including those who exhaled methane. We categorized participants into low- and high-exhaled hydrogen groups based on the median exhaled hydrogen concentration of 6.13 ppm and matched background factors by propensity score matching for age, body mass index, and defecation habits. In the high exhaled hydrogen group, intestinal butyrate-producing bacteria such as

Indexed as

breath hydrogenbreath methanegut microbiotanutrients

Identifiers

PMID41492375
PMCPMC12765536

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.