Evidence map›Paper›PMID 41492372›Full record

ArticleBioscience of microbiota, food and health2026

An altered gut microbiota is associated with anthropometric and biochemical changes in a prediabetes Mexican cohort.

Fernando Suárez-Sánchez, Luis Fernando Alvarado-Vera, Valentina Tremaroli, Graciela Castro-Escarpulli, Jesús Peralta-Romero, Miguel Cruz-López

Abstract read
In one paragraph

Article in Bioscience of microbiota, food and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fernando Suárez-SánchezUnidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Instituto Mexicano del Seguro Social, México City, México.
Luis Fernando Alvarado-VeraUnidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Instituto Mexicano del Seguro Social, México City, México.
Valentina TremaroliWallenberg Laboratory, Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Graciela Castro-EscarpulliWallenberg Laboratory, Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Jesús Peralta-RomeroLaboratorio de Investigación Clínica y Ambiental, Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, México City, México.
Miguel Cruz-LópezUnidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Instituto Mexicano del Seguro Social, México City, México.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An altered gut microbiota is considered to be an environmental factor contributing to the pathogenesis of various diseases, including metabolic disorders. In this study, we identified changes in the composition of the fecal microbiota of Mexican individuals with prediabetes and analyzed their influences on variables related to this metabolic disorder. Bacterial DNA was extracted from feces of normoglycemic and prediabetes individuals, followed by sequencing of the V4 16S rDNA. Clinical variables were correlated with bacterial abundance and diversity indexes. LEfSe analysis was used to identify relevant bacteria in normoglycemic and prediabetes individuals. Relationships between bacterial clusters and clinical data were assessed with weighted correlation network analysis (WGCNA). Bacterial diversity was positively correlated with anthropometric variables in the control group, while in individuals with prediabetes, it was negatively correlated with the insulin concentration and homeostatic model assessment of insulin resistance (HOMA-IR). We also observed that the microbiota in prediabetes individuals had a higher prevalence of

Indexed as

dysbiosisprediabetesRalstonia

Identifiers

PMID41492372
PMCPMC12765534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.