ArticleHealth science reports2026
Uric Acid, Arterial Stiffness and Blood Pressure: A Population-Based Cohort Study.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Uric Acid, Arterial Stiffness and Blood Pressure: A Population-Based Cohort Study.Health science reports · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aim: Serum uric acid (SUA) has long been linked to elevated blood pressure (BP) in observational clinical studies. Nonetheless, data regarding the correlation between SUA and BP are controversial in randomized controlled trials and mendelian randomization research. Furthermore, it is yet unknown if there is a reciprocal relationship between SUA and BP. This study was conducted to explore the temporal relationship between SUA and BP and related risk factors. Methods: In this cohort study, 27,581 participants free of hypertension and cardiovascular disease from 2010 to 2016 in the Kailuan study were included. Cross-lagged studies with repeated evaluation of BP and SUA were applied to identify the temporal relationship between SUA and BP. The brachial-ankle pulse wave velocity (baPWV) and high-sensitivity C-reactive protein (hs-CRP) were conducted to evaluate the mediation impact on the correlation between SUA and BP among 6761 participants via mediation analysis. Results: The cross-lagged path coefficient of baseline SUA and follow-up systolic BP (β2) was 0.06 (95% CI, 0.03-0.08) in the participants with the age of ≤ 45 ( Conclusion: SUA may be a precursor to raised BP in young men, vascular stiffness mediated the positive correlation between BP and SUA. Trial Registration: ChiCTR-TNC-11001489.
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