Evidence map›Paper›PMID 41492310›Full record

ArticleOsteoarthritis and cartilage open2026

Osteoarthritis physical activity care pathway: Results of an exploratory trial.

Kelli D Allen, Katie F Huffman, Leigh F Callahan, Natalie Fullenkamp, Yvonne M Golightly, Derek P Hales, Amanda E Nelson, Stephanie Ntim, Ami Pathak, Jennifer Rees and 3 more

Abstract read
In one paragraph

Article in Osteoarthritis and cartilage open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kelli D AllenThurston Arthritis Research Center, University of North Carolina at Chapel Hill, USA.
Katie F HuffmanThurston Arthritis Research Center, University of North Carolina at Chapel Hill, USA.
Leigh F CallahanThurston Arthritis Research Center, University of North Carolina at Chapel Hill, USA.
Natalie FullenkampCenter of Innovation to Accelerate North Carolina Clinical and Translational Sciences Institute, Durham VA Healthcare System, USA.
Yvonne M GolightlyCollege of Allied Health Professions, University of Nebraska Medical Center, USA.
Derek P HalesCenter for Health Promotion and Disease Prevention, University of North Carolina at Chapel Hill, USA.
Amanda E NelsonThurston Arthritis Research Center, University of North Carolina at Chapel Hill, USA.
Stephanie NtimDepartment of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Ami PathakUnviersity of North Carolina Health Chatham, Siler City, NC, USA.
Jennifer ReesNorth Carolina Translational and Clinical Sciences Institute, University of North Carolina at Chapel Hill, USA.
Riya VasaThurston Arthritis Research Center, University of North Carolina at Chapel Hill, USA.
Maihan B VuCenter for Health Promotion and Disease Prevention, University of North Carolina at Chapel Hill, USA.
Rebecca J ClevelandThurston Arthritis Research Center, University of North Carolina at Chapel Hill, USA.

Funding

UNC Core Center for Clinical ResearchP30AR072580 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEIGH Fleming CALLAHAN, Amanda E Nelson · 2019 to 2026
$6.1M
NIAMS NIH HHS P30 AR072580
6 · The paper itself

Abstract

Objective: To conduct an exploratory randomized controlled trial of a physical activity intervention for individuals with osteoarthritis (OA) involving telephone-delivered coaching, activity self-monitoring, and connection with resources to support activity (Osteoarthritis Physical Activity Care Pathway; OA-PCP). Methods: Older adults (age ≥65 years) with symptomatic hip or knee OA and comorbid health conditions (N ​= ​240) were randomized to OA-PCP or an attention control (AC) condition. OA-PCP included coaching calls at baseline and at 3-month intervals through 12 months, as well as email-delivered content. The ACgroup received calls and emails focused on OA education. The primary outcome was minutes of moderate to vigorous physical activity (MVPA) per week, measured at baseline, 6-months and 12-months via accelerometer. Secondary outcomes included other physical activity metrics and the Western Ontario and McMaster Universities Osteoarthritis Index pain and function subscales. Linear mixed regression was used to estimate between-group differences from baseline to follow-up time points. Results: At 6-month and 12-month follow-up, the changes in weekly MVPA favored the OA-PCP by 9.5 ​min (95 ​% Confidence Interval -6.7, 25.8; p ​= ​0.252) and 12.3 ​min (95 ​% Confidence Interval -3.8, 28.4; p ​= ​0.136), respectively, but differences were not statistically or clinically significant. There were no significant between-group differences in secondary outcomes other than steps per day at 12-months. Conclusions: A more intensive intervention approach may be needed to enhance physical activity among older adults with OA and comorbid health conditions.

Indexed as

FunctionOsteoarthritisPainPhysical activityRandomized controlled trial

Identifiers

PMID41492310
PMCPMC12765192

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.