Evidence map›Paper›PMID 41492203›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2026

Silent Partners in the Mill: Unveiling the Role of Additives in Mechanochemical Synthesis.

Johanna Breinsperger, Nika Podlesnik, Francesco Mele, Michael Schnürch

Abstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Johanna BreinspergerInstitute of Applied Synthetic Chemistry, TU, Vienna, Wien, Austria.ORCID https://orcid.org/0009-0007-4683-4085
Nika PodlesnikInstitute of Applied Synthetic Chemistry, TU, Vienna, Wien, Austria.ORCID https://orcid.org/0009-0006-7966-5209
Francesco MeleSynCat Lab, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy.ORCID https://orcid.org/0000-0001-6921-1963
Michael SchnürchInstitute of Applied Synthetic Chemistry, TU, Vienna, Wien, Austria.ORCID https://orcid.org/0000-0003-2946-9294

Funding

FFG
6 · The paper itself

Abstract

Mechanochemistry has attracted significant attention as a sustainable and efficient alternative to solution-based synthesis, offering the advantage of solvent-free conditions or the use of only minor amounts of solvent. Many established mechanochemical transformations rely on the use of additives-a strategy broadly referred to as additive-assisted grinding. The most employed additives are liquids (liquid-assisted grinding (LAG)), ionic solids, and non-ionic additives. Additionally, ionic liquids (ionic liquid-assisted grinding (IL-AG)), piezoelectric, or mechanoluminescent materials can be used. This review provides an overview of additive-assisted organic synthetic transformations under mechanochemical conditions, highlighting the roles, advantages, and limitations of additives, as well as emerging trends from recent literature.

Indexed as

additiveenergy transfermechanochemistrysalt effectsolvent free

Identifiers

PMID41492203
PMCPMC12958107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.