Evidence map›Paper›PMID 41492140›Full record

ArticleMicrosurgery2026

Flap Choice in Gender Affirming Phalloplasty Affects Postoperative Complication Rates.

Ellen Wang, Bennett Cleff, Anthony Basta, Jackson C Green, Kylie R Swiekatowski, Paul Won, Kris Slaughter, Rachel Goldstein, Klara Sputova, Daniel Freet

Abstract read
In one paragraph

Article in Microsurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ellen WangDivision of Plastic and Reconstructive Surgery, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.ORCID https://orcid.org/0000-0001-7800-9273
Bennett CleffDivision of Plastic and Reconstructive Surgery, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Anthony BastaDivision of Plastic and Reconstructive Surgery, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Jackson C GreenDivision of Plastic and Reconstructive Surgery, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Kylie R SwiekatowskiDivision of Plastic and Reconstructive Surgery, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Paul WonDivision of Plastic and Reconstructive Surgery, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Kris SlaughterDivision of Plastic and Reconstructive Surgery, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Rachel GoldsteinDivision of Plastic and Reconstructive Surgery, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Klara SputovaDivision of Plastic and Reconstructive Surgery, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
Daniel FreetDivision of Plastic and Reconstructive Surgery, University of Iowa Health Care, Iowa City, Iowa, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhalloplasty plays an important role in female-to-male (FTM) gender affirmation surgery to create a neophallus that prioritizes aesthetic and functional outcomes. Patients have a variety of flap choices for phalloplasty, but they can often come with complications. This study aimed to evaluate the impact of flap choice on the rate of complications in phalloplasty.

methodsThis retrospective cohort study was conducted at a single institution of adult patients who underwent either phalloplasty with radial forearm (RFFF), anterolateral thigh (ALT) pedicled flaps, or pedicled abdominal flaps. Complications of urethral stricture, urethral fistula, necrosis of neophallus, infection, wound dehiscence, and flap loss were analyzed.

resultsA total of 57 patients underwent phalloplasty. RFFF was used in 25 (43.9%) patients, ALT flaps in 10 (17.5%) patients, and pedicled abdominal flaps in 22 (38.6%) patients. The overall complication rate was 61.4%. RFFF had the highest complication rate (80%), followed by ALT (60%) and pedicled abdominal flaps (40.9%) (p = 0.023). RFFF had the highest rate of urological complications (60%) (p = 0.013), including fistulas (48%) compared to ALT (20%) and pedicled abdominal flaps (9.1%) (p = 0.011), and urethral strictures (44%) compared to ALT (20%) and pedicled abdominal flaps (22.7%) (p = 0.24). RFFF required more reoperations (64%) compared to ALT (40%) and pedicled abdominal flaps (31.8%) (p = 0.082). On multivariate analysis, patients experiencing complications were more likely to have blood thinners (OR = 1.85, 95% CI: 1.05-3.25, p = 0.039) and less likely to undergo staged phalloplasty (OR = 0.91, 95% CI: 0.32-2.61). DISCUSSION: Flap choice for phalloplasty requires careful consideration between patients and providers. Pedicled abdominal flaps were associated with fewer complications, such as fistulas, urethral strictures, and reoperations. However, patients may opt for RFFF to maximize aesthetic outcomes despite such risks. Insight into clinical outcomes is vital to both surgeons and their patients to enhance the shared decision-making process.

Indexed as

Gender-Affirming SurgeryPenisPostoperative ComplicationsSurgical FlapsAdultFemaleHumansMaleMiddle AgedPhalloplastyRetrospective StudiesTreatment OutcomeYoung Adultfemale to malefree flapgender affirming surgeryphalloplastyplastic surgeryurethroplasty

Identifiers

PMID41492140
PMCPMC12770917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.