ArticleNPJ microgravity2026
A new strategy for constructing microgravity culture environment via gas-liquid coupled oscillatory flow field.
Article in NPJ microgravity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The mainstream Rotating Cell Culture System (RCCS) simulates microgravity via three-dimensional dynamic rotation, which differs from true space microgravity in physical mechanisms. In this context, the present investigation innovatively proposes a new microgravity simulation strategy based on Einstein's equivalence principle-establish a stable and controllable quasi-free-fall flow field environment by constructing a gas-liquid coupled oscillatory system inside the U-tube. Based on the analysis of the physical modeling of the oscillating flow field in the vertical U-tube and the CFD-VOF gas-liquid coupling simulation experiments with parameters (D = 15 mm, R/D = 1.3) shown that in each oscillation period, 71% of the liquid will lose weight in two vertical sections, and when the liquid at the maximum volume ratio the average weight loss peak value is 0.02 g, achieving spatial low microgravity (10
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