Evidence map›Paper›PMID 41492024›Full record

ArticleEuropean radiology2026

Long-term outcomes and prognostic factors following microwave ablation vs surgical resection for primary hyperparathyroidism.

Ying Wei, Zhenlong Zhao, Jie Wu, Shiliang Cao, Na Yu, Wenjia Cai, Lili Peng, Yan Li, Shuqi Li, Ming'an Yu

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ying WeiDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Zhenlong ZhaoDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Jie WuDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Shiliang CaoDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Na YuDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Wenjia CaiDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Lili PengDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Yan LiDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Shuqi LiDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Ming'an YuDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China. yma301@163.com.ORCID http://orcid.org/0000-0003-0797-4564

Funding

National High Level Hospital Clinical Research Funding 2025-NHLHCRF-JBGS-A-WZ-01National High Level Hospital Clinical Research Funding, Elite Medical Professionals Project of China-Japan Friendship Hospital ZRJY2023-GG19National Natural Science Foundation of China 62176268
6 · The paper itself

Abstract

objectiveTo compare the long-term efficacy and safety of microwave ablation (MWA) vs surgical resection (SR) in patients with primary hyperparathyroidism (PHPT) over five years. MATERIALS AND

methodsThis retrospective study evaluated 172 consecutive patients with PHPT (88 underwent MWA, 84 underwent SR) from 2015 to 2025. The median follow-up was 70.7 months (interquartile range [IQR], 42.6-96.3) in the MWA group and 77.7 months (IQR, 56.5-113.8) in the SR group. Primary outcomes included first-treatment success rate (biochemical normalization after a single procedure without additional interventions), cure rate, and long-term remission rate. Clinical, laboratory, and imaging parameters were analyzed to identify prognostic indicators. Multivariable regression adjusted for key baseline variables.

resultsNo significant differences were observed in overall or 1-, 3-, and 5-year long-term remission rates (all p > 0.05) between MWA and SR groups (5-year rate, 77.2% vs 83.1%, log-rank p = 0.78). After adjustment, treatment modality was not associated with cure rate (odds ratio [OR], 1.92; 95% confidence interval [CI], 0.59-6.28; p = 0.28) or long-term remission (hazard ratio [HR], 0.79; 95% CI: 0.18-3.53; p = 0.75). A single parathyroid nodule predicted cure (OR, 3.70; 95% CI: 1.02-3.49; p = 0.048), while higher serum creatinine predicted remission loss (HR, 1.05; 95% CI: 1.01-1.09; p = 0.02). Complication rates were comparable between groups (6.8% vs 3.6%, p = 0.30).

conclusionMWA provides long-term efficacy comparable to SR for PHPT over five years. Solitary parathyroid nodules and normal renal function are associated with better outcomes regardless of treatment modality. KEY POINTS: Question Can MWA achieve long-term efficacy and safety comparable to SR in patients with PHPT? Findings Five-year remission was similar between MWA and SR = 0.78); major complication rates also did not differ. Solitary nodules predicted cure, while elevated creatinine was linked to remission loss. Clinical relevance MWA offers a minimally invasive alternative to SR in selected patients with PHPT, providing comparable five-year biochemical remission with a similar safety profile.

Indexed as

Ablation TechniquesHyperparathyroidism, PrimaryMicrowavesAgedFemaleHumansMaleMiddle AgedParathyroidectomyRetrospective StudiesTreatment OutcomeIntact parathyroid hormoneLong-termMicrowave ablationPrimary hyperparathyroidismSurgical resection

Identifiers

PMID41492024

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.