Evidence map›Paper›PMID 41491914›Full record

ArticleBlood cancer journal2026

Frequent and clinically relevant germline DNA repair gene variants in young and familial myeloproliferative neoplasms.

Robert Meyer, Maria Jimena Rodriguez, Madeline Caduc, Kim Kricheldorf, Matthias Begemann, Florian Kraft, Isabel Spier, Daniela Dey, Nergis Güzel, Kerstin Becker and 10 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood cancer journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. JAK2Leukemia · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Robert Meyer *Center for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany. rmeyer@ukaachen.de.ORCID http://orcid.org/0000-0002-5693-2216
Maria Jimena Rodriguez *Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.ORCID http://orcid.org/0000-0003-4773-1444
Madeline CaducCenter for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Kim KricheldorfCenter for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Matthias BegemannCenter for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.ORCID http://orcid.org/0000-0002-4659-8437
Florian KraftCenter for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.ORCID http://orcid.org/0000-0002-5324-9155
Isabel SpierNational Center for Hereditary Tumour Syndromes, University Hospital Bonn, and Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Bonn, Germany.
Daniela DeyCenter for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Nergis GüzelCenter for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.ORCID http://orcid.org/0009-0002-1030-2179
Kerstin BeckerWest German Genome Center (WGGC), Cologne, Germany.
Julian BaumeisterCenter for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Marcelo A S de ToledoCenter for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Susanne IsfortCenter for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.
Ulrich GermingDepartment of Hematology, Oncology and Clinical Immunology, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Stefan AretzNational Center for Hereditary Tumour Syndromes, University Hospital Bonn, and Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Bonn, Germany.
Tim H BrümmendorfCenter for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.ORCID http://orcid.org/0000-0002-9677-3723
Ingo KurthCenter for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.ORCID http://orcid.org/0000-0002-5642-8378
Miriam ElbrachtCenter for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.ORCID http://orcid.org/0000-0001-5088-1369
Lino L TeichmannDepartment of Medicine III, University Hospital Bonn, Bonn, Germany.
Steffen KoschmiederCenter for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany.ORCID http://orcid.org/0000-0002-1011-8171

Funding

Deutsche Krebshilfe (German Cancer Aid) 70114726
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41491914
PMCPMC12770421

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.