ArticleInternational journal of clinical oncology2026
Sequential changes in conditional survival of patients following surgical resection of colorectal cancer and indicators for follow-up beyond 5 years.
Article in International journal of clinical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe evolving prognosis of colorectal cancer (CRC) over extended periods following surgery has not been comprehensively characterized. This study aimed to delineate long-term patterns in conditional survival (CS), evaluate the changing relevance of CRC recurrence surveillance versus management of fatal non-cancer conditions, and suggest follow-up indicators tailored to postoperative duration.
methodsWe examined trends in conditional overall survival (cOS), disease-specific survival (cDSS), and non-disease-specific survival (cNDSS) by tumor stage in 2,996 patients (stage 0-IV) who underwent surgical resection for CRC. Furthermore, we conducted a multivariate analysis in a cohort of 1,529 patients surviving more than 5 years to identify predictors of long-term survival.
resultsOver a median observation period of 60.4 months, 745 deaths were recorded (478 CRC-related, 243 unrelated to CRC, and 24 unknown). Stage-wise CS analyses revealed crossover points of cDSS and cNDSS at 3 years post-surgery in stage II and at 6 years in stages III/IV. Multivariate analysis identified age ≥ 80, CEA ≥ 5.0 ng/mL, CA19-9 ≥ 37.0 U/mL, albumin ≤ 4.1 g/dL, anemia, RDW ≥ 14.9%, and platelet count ≤ 150 × 10
conclusionsThe importance of CRC recurrence surveillance was most prominent within the first 3 years after surgery in stage II and within 6 years in stages III/IV. Our findings underscore the need to customize surveillance strategies based on duration since surgery and indicate that the aforementioned clinical parameters may serve as useful markers in 5-year survivors.
Indexed as
Identifiers
41491896What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.