Evidence map›Paper›PMID 41491847›Full record

ArticleScientific reports2026

Association of diurnal blood pressure patterns with heart rate variability and retinopathy in patients with essential hypertension.

Fengping Gong, Hui Li, Tianfeng Huang, Chen Gao

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fengping GongFirst School of Clinical Medical, Gansu University of Chinese Medicine, Lanzhou, 730000, Gansu, China.
Hui LiDepartment of General Practice, The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army, Lanzhou, 730050, Gansu, China.
Tianfeng HuangFirst School of Clinical Medical, Gansu University of Chinese Medicine, Lanzhou, 730000, Gansu, China.
Chen GaoFirst School of Clinical Medical, Gansu University of Chinese Medicine, Lanzhou, 730000, Gansu, China. gc2006418@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the association of different diurnal blood pressure patterns with heart rate variability (HRV) and hypertensive retinopathy (HR) risk in essential hypertension patients. A total of 181 patients (Jan 2023-Jun 2025) were grouped by nocturnal systolic blood pressure fall rate (SBPF): dipper (n = 57, 10%≤SBPF < 20%), non-dipper (n = 62, 0 ≤ SBPF < 10%), reverse-dipper (n = 62, SBPF < 0%). Ambulatory blood pressure (BP), HRV indices, and HR detection rate were compared. Reverse-dipper had higher nocturnal SBP (nSBP), 24-hour SBP (24hSBP) than the other two groups (all P < 0.05), and higher nocturnal DBP (nDBP) than dipper (P = 0.002). Dipper's HRV indices (SDNN, SDANN, RMSSD, PNN50, LF, HF) were better than non-dipper (P < 0.05); SDNN, SDANN, LF were better than reverse-dipper (all P < 0.001). Reverse-dipper's LF/HF was lower than others (P < 0.05). HR detection rates: 3.5% (dipper), 46.8% (non-dipper), 50.0% (reverse-dipper) (P < 0.001). Multivariable regression: BMI (OR = 1.131) was an independent risk factor; dipper (vs. reverse-dipper, OR = 0.031) was protective (P < 0.05). Reverse-dipper has the highest nocturnal BP load, dipper the most favorable (better autonomic regulation). Ambulatory BP monitoring and BMI control are crucial to reduce target organ damage.

Indexed as

Blood PressureCircadian RhythmEssential HypertensionHeart RateHypertensive RetinopathyAdultAgedBlood Pressure Monitoring, AmbulatoryFemaleHumansMaleMiddle AgedRisk FactorsAutonomic nervous functionDiurnal blood pressure patternHeart rate variabilityHypertensionHypertensive retinopathy

Identifiers

PMID41491847
PMCPMC12770316

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.