Article in Nature chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
6 authors.
Zheng RuanDepartment of Structural Biology, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0002-4412-4916
Junuk LeeDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, USA.
Yangyang LiDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, USA.
Ian J OrozcoDepartment of Structural Biology, Van Andel Institute, Grand Rapids, MI, USA.
Juan DuDepartment of Structural Biology, Van Andel Institute, Grand Rapids, MI, USA. juan.du@northwestern.edu.ORCID 0000-0003-1467-1203
Wei LüDepartment of Structural Biology, Van Andel Institute, Grand Rapids, MI, USA. wei.lu@northwestern.edu.ORCID 0000-0002-3009-1025
Funding
Structural and Functional Studies of the TRPM4 and TRPM5 ChannelsR01HL153219 · NHLBI · VAN ANDEL RESEARCH INSTITUTE · PI Wei Lu · 2020 to 2026
$3.9M
Structural Basis of Nociceptor Channel TRPM3 gating and pharmacologyR01NS129804 · NINDS · VAN ANDEL RESEARCH INSTITUTE · PI Juan Du · 2023 to 2026
$2.8M
Structural and functional studies of the TRPM2 channelR01NS111031 · NINDS · VAN ANDEL RESEARCH INSTITUTE · PI DU, JUAN · 2019 to 2023
$2.7M
Structural and functional studies of CALHM channelsR01NS112363 · NINDS · VAN ANDEL RESEARCH INSTITUTE · PI LU, WEI · 2020 to 2024
$2.3M
Elucidating structures and molecular mechanisms of Pannexin channelsR35GM138321 · NIGMS · VAN ANDEL RESEARCH INSTITUTE · PI LU, WEI · 2020 to 2024
$2.3M
Structural and Functional Studies on Proton-activated Chloride (PAC) ChannelR00NS128258 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI Zheng Ruan · 2024 to 2026
$740k
American Heart Association (American Heart Association, Inc.) 20POST35120556NHLBI NIH HHS R01 HL153219NIGMS NIH HHS R35 GM138321NINDS NIH HHS R00 NS128258NINDS NIH HHS R01 NS111031NINDS NIH HHS R01 NS112363NINDS NIH HHS R01 NS129804U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL153219U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R35GM138321U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R00NS128258U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS111031U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS112363U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS129804
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
A single allosteric site merges activation, modulation and inhibition in TRPM5. · full record | OpenQuestion