Evidence map›Paper›PMID 41491793›Full record

ArticleNPJ science of food2026

Distinct transmission routes of Salmonella enterica serovars during pig growth on farms.

Yaming Hong, Hui Liu, Xiaojie Wang, Ruoyun Ji, Qilong Hou, Hui Zhang, Yang Jiao, Qiuchun Li, Zhenyu Wang

Abstract read
In one paragraph

Article in NPJ science of food, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yaming Hong *Jiangsu Key Lab of Zoonosis/Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.
Hui Liu *Jiangsu Key Lab of Zoonosis/Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.
Xiaojie Wang *Jiangsu Key Lab of Zoonosis/Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.
Ruoyun JiJiangsu Key Lab of Zoonosis/Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.
Qilong HouJiangsu Key Lab of Zoonosis/Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.
Hui ZhangJiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base of MOST, Jiangsu Academy of Agricultural Sciences, Nanjing, China.
Yang JiaoDepartment of Microbiology and Vaccinology, Center for Global Health, School of Public Health, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, China. yangjiao@njmu.edu.cn.
Qiuchun LiJiangsu Key Lab of Zoonosis/Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China. qcli@yzu.edu.cn.
Zhenyu WangJiangsu Key Lab of Zoonosis/Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China. wangzhenyu@yzu.edu.cn.

Funding

National Key Research and Development Program of China 2024YFE0198800
6 · The paper itself

Abstract

Non-typhoidal Salmonella enterica is a major foodborne pathogen, with pigs and pig-derived products serving as key transmission sources of human infection. In this study, we applied whole-genome sequencing (WGS) to investigate the prevalence, transmission dynamics and antimicrobial resistance of Salmonella throughout the pig growing process on four closely related pig farms in China. Core-genome single nucleotide polymorphism (cgSNP) analysis has been widely used to determine the genetic relationships among Salmonella isolates from animals and animal-derived foods. To our knowledge, this is the first study to apply cgSNP analysis for epidemiological tracing of Salmonella transmission across interconnected pig farms in China. A total of 1,211 samples were collected from one breeding farm and three commercial farms in China, yielding 249 Salmonella isolates with an overall prevalence rate of 20.6%. Serotyping and genomic analysis determined five serovars, primarily S. Rissen, S. Derby, and S. 1,4,[5],12:i:-. cgSNP analysis further classified S. Rissen, S. Derby, and S. 1,4,[5],12:i:- into different clusters and revealed different transmission routes. Antimicrobial susceptibility test (AST) showed that all major serovars exhibited similar multidrug resistance to ampicillin, tetracycline, and sulfamethoxazole-trimethoprim. These findings demonstrate that different Salmonella serovars spread via distinct transmission routes but share common antimicrobial resistance patterns in pigs, emphasizing the need for targeted control measures across pig production chain to reduce the public health risks associated with antimicrobial-resistant Salmonella.

Identifiers

PMID41491793
PMCPMC12873352

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.