Evidence map›Paper›PMID 41491746›Full record

ArticleSurgery today2026

Clinical significance of preoperative oral frailty and malnutrition in predicting the surgical outcomes of Gastrointestinal cancers.

Yutaro Shimizu, Takuya Shiraishi, Yuta Shibasaki, Takuhisa Okada, Katsuya Osone, Akiharu Kimura, Akihiko Sano, Makoto Sakai, Ken Shirabe, Hiroshi Saeki

Abstract read
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In one paragraph

Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yutaro ShimizuDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showa-Machi, Maebashi, 371-8511, Gunma, Japan.
Takuya ShiraishiDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showa-Machi, Maebashi, 371-8511, Gunma, Japan. m04037ts@jichi.ac.jp.ORCID http://orcid.org/0000-0003-3543-1874
Yuta ShibasakiDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showa-Machi, Maebashi, 371-8511, Gunma, Japan.
Takuhisa OkadaDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showa-Machi, Maebashi, 371-8511, Gunma, Japan.
Katsuya OsoneDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showa-Machi, Maebashi, 371-8511, Gunma, Japan.
Akiharu KimuraDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showa-Machi, Maebashi, 371-8511, Gunma, Japan.
Akihiko SanoDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showa-Machi, Maebashi, 371-8511, Gunma, Japan.
Makoto SakaiDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showa-Machi, Maebashi, 371-8511, Gunma, Japan.
Ken ShirabeDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showa-Machi, Maebashi, 371-8511, Gunma, Japan.
Hiroshi SaekiDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showa-Machi, Maebashi, 371-8511, Gunma, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn this study, we aimed to investigate the association between preoperative oral frailty, nutritional status, and postoperative complications in patients who underwent curative gastrointestinal (GI) cancer surgery.

methodsWe retrospectively analyzed 181 patients who underwent curative resection for GI malignancies between April 2022 and March 2024. Oral frailty and nutritional status were assessed using the Oral Frailty Index-8 (OFI-8) and Mini Nutritional Assessment-Short Form (MNA-SF) through structured, nurse-administered preoperative questionnaires. Complications were defined as Clavien-Dindo grade ≥ 2. Logistic regression analyses were used to identify independent risk factors.

resultsComplications occurred in 30.9% of the participants. Participants with both oral frailty (OFI-8 ≥ 4) and a risk of malnutrition (MNA-SF ≤ 11) had the highest complication rate (55.2%). In the multivariate analysis, the combination of these two factors was an independent predictor of postoperative complications (odds ratio: 3.16, p = 0.01).

conclusionsPreoperative oral frailty and malnutrition are significant predictors of postoperative complications in patients with GI cancers. A simple composite score combining OFI-8 and MNA-SF may improve risk stratification and inform multidisciplinary preoperative care strategies to optimize surgical outcomes.

Indexed as

Digestive System Surgical ProceduresFrailtyGastrointestinal NeoplasmsMalnutritionPostoperative ComplicationsAgedAged, 80 and overFemaleHumansMaleMiddle AgedNutritional StatusNutrition AssessmentPreoperative CarePreoperative PeriodRetrospective StudiesGastrointestinal cancerMalnutritionMNA-SF (Mini nutritional Assessment–Short form)Oral frailtyPostoperative complicationsPredictive modelPreoperative assessmentRisk score

Identifiers

PMID41491746

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.