Evidence map›Paper›PMID 41491709›Full record

ArticleParasites & vectors2026

Differences in metavirome among Aedes albopictus, Culex tritaeniorhynchus, and Anopheles sinensis in Jiangxi Province, China.

Xin Ran, Dajin Xiao, Yangbowen Wu, Yong Shi, Shiwen Liu, Yu Bai, Qiang Zhang, Lan Liu, Qian Liu, Jianxiong Li and 1 more

Abstract read
In one paragraph

Article in Parasites & vectors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Xin RanLaboratory of Viral Infectious Disease, The Key Laboratory of Important and Emerging Viral Infectious Diseases of Jiangxi Health Commission, Jiangxi Provincial Center for Disease Control and Prevention, Nanchang, China.
Dajin XiaoLaboratory of Viral Infectious Disease, The Key Laboratory of Important and Emerging Viral Infectious Diseases of Jiangxi Health Commission, Jiangxi Provincial Center for Disease Control and Prevention, Nanchang, China.
Yangbowen WuLaboratory of Viral Infectious Disease, The Key Laboratory of Important and Emerging Viral Infectious Diseases of Jiangxi Health Commission, Jiangxi Provincial Center for Disease Control and Prevention, Nanchang, China.
Yong ShiLaboratory of Viral Infectious Disease, The Key Laboratory of Important and Emerging Viral Infectious Diseases of Jiangxi Health Commission, Jiangxi Provincial Center for Disease Control and Prevention, Nanchang, China.
Shiwen LiuLaboratory of Viral Infectious Disease, The Key Laboratory of Important and Emerging Viral Infectious Diseases of Jiangxi Health Commission, Jiangxi Provincial Center for Disease Control and Prevention, Nanchang, China.
Yu BaiJiangxi International Travel Healthcare Center, Nanchang, China.
Qiang ZhangJiangxi International Travel Healthcare Center, Nanchang, China.
Lan LiuJiangxi International Travel Healthcare Center, Nanchang, China.
Qian LiuJiangxi International Travel Healthcare Center, Nanchang, China.
Jianxiong LiLaboratory of Viral Infectious Disease, The Key Laboratory of Important and Emerging Viral Infectious Diseases of Jiangxi Health Commission, Jiangxi Provincial Center for Disease Control and Prevention, Nanchang, China. cmuljx@126.com.
Minghui ZhaoJiangxi International Travel Healthcare Center, Nanchang, China. zhaomhmosquito@126.com.

Funding

Key Scientific and Technological Innovation Projects of the Jiangxi Provincial Health Commission 2025ZD008Nanchang Customs Technology Project 2022HK4005
6 · The paper itself

Abstract

backgroundMosquito metavirome research aims to comprehensively characterize the diversity of mosquito-associated viruses, particularly focusing on insect-specific viruses (ISVs) and their potential interactions with arboviruses of public health concern. Advances in next-generation sequencing (NGS) have significantly expanded our understanding of the viromic complexity within mosquito populations, revealing numerous novel viral species and genera. These studies not only contribute to viral taxonomy and evolutionary biology but also provide critical insights into the ecological dynamics between mosquitoes and their viromes.

methodsNGS was employed to characterize the metavirome of three epidemiologically significant mosquito vectors, Aedes albopictus, Culex tritaeniorhynchus, and Anopheles sinensis in Jiangxi Province, China. This study integrated bioinformatic workflows to conduct comparative analyses of viral composition and biological significance.

resultsAn analysis of the metavirome of three mosquito species in Jiangxi Province revealed 86 viruses. Of these, 49 belonged to 19 established families, while the remaining 37 were unclassified. The unclassified viruses had the highest relative abundance. The known virus families with relatively high abundances among the three mosquito species were: Solemoviridae, Xinmoviridae, Phasmaviridae, Flaviviridae, Rhabdoviridae, Peribunyaviridae and Orthomyxoviridae. Although the Shannon and Simpson diversity indices showed no significant differences between the three species (p > 0.05), substantial compositional divergence was observed in the "top 30 viruses." The most frequently detected viruses in the Ae. albopictus population include High Island virus, Usinis virus, Sichuan mosquito sobemo-like virus, Guangzhou sobemo-like virus, Barstukas virus, Piry virus (PIRYV), Aedes flavivirus (AEFV), and Aedes albopictus anphevirus (AealbAV). The most frequently detected viruses in the Cx. tritaeniorhynchus population include Hubei mosquito virus 2, Quang Binh virus (QBV), Culex tritaeniorhynchus rhabdovirus (CTRV), Yongsan sobemo-like virus 1 (YSLV1), Bat sobemovirus (BSV), Wuhan Mosquito Virus 2 (WMV2), and Culex pseudovishnui bunya-like virus (CPBV). The most frequently detected viruses in the An. sinensis population include Hubei reo-like virus 12, Xincheng mosquito virus (XCV), Wuhan mosquito virus 1 (WMV1), and Wuhan mosquito virus 5 (WMV5).

conclusionsThe most frequently detected virus profiles of the three most important mosquito species for epidemiology in Jiangxi Province, Ae. albopictus, Cx. tritaeniorhynchus, and An. sinensis, exhibit evident differences. Further validation of the biological characteristics, pathogenicity, vector competence, and host relationships of the identified viruses (including ISVs) is required to gain a comprehensive understanding of their roles in host-virus interactions. This will provide theoretical support for vector control efforts in Jiangxi Province.

Indexed as

AedesAnophelesCulexInsect VirusesMosquito VectorsViromeAnimalsChinaHigh-Throughput Nucleotide SequencingPhylogenyAe. albopictusAn. sinensisCx. tritaeniorhynchusMetavirome

Identifiers

PMID41491709
PMCPMC12781663

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.