ArticleMedical physics2026
Investigation of inter-source and intra-source spectral variations in an electronic brachytherapy source using spectral measurements and Monte Carlo simulations.
Article in Medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
7 authors.
Funding
Abstract
backgroundThe Xoft electronic brachytherapy source is commonly used to treat superficial lesions and tumors located at shallow depths. However, uncertainties in material composition and geometry, mainly arising due to the manual assembly of the x-ray tube components, contribute to inter-source variability in the tube output spectrum. In addition, aging of the x-ray tube may lead to intra-source variability in the tube spectrum. PURPOSE: To investigate the inter- and intra-source variability of the spectrum for the Xoft S7500 model experimentally and through simulations, as well as to study the impact of this variability on dosimetry.
methodsThe Amptek X123 CdTe x-ray spectrometer was used to measure the spectrum of the Xoft S7500 source model. First, the spectrometer was calibrated using
resultsThe calibration line was obtained to correspond the detector channels to the energy in keV using linear regression. Escape peak and background corrections were performed on the spectrum, and the counts in the K-edges of cadmium (26.7 keV) and tellurium (31.8 keV) were readjusted so that the silver peaks were more clearly resolved. Intra-source variability demonstrated consistent peak resolution for tungsten, yttrium, and silver, with a coefficient of variation (CV) ranging from 0.5% to 9.8%. Inter-source variability highlighted significant differences between tip and side measurements, with up to 13.5% variation. Simulated spectra revealed the impact of material composition on the characteristic peak intensities, with the intensity of the peaks in the measured spectra lying between simulated spectra in the case of higher and lower percentage limits of yttrium and silver present in the material composition. Depth-dose simulations showed minimal differences (<1.2%) between material compositions.
conclusionsThis study comprehensively compared the measured and simulated spectra of the Xoft S7500 source model. The differences in the depth-dose curves are within 2% as recommended by the AAPM TG-56
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