Evidence map›Paper›PMID 41491590›Full record

ArticleMolecular ecology2026

PoolSeq Genome-Wide Association Studies and Microbial Signature Analyses Identify Novel Candidates Associated With Pyrethroid Resistance Evolution in Anopheles funestus in Cameroon.

Mahamat Gadji, Jonas A Kengne-Ouafo, Magellan Tchouakui, Murielle J Wondji, Leon M J Mugenzi, Jack Hearn, Boyomo Onana, Charles S Wondji

Abstract read
In one paragraph

Article in Molecular ecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mahamat GadjiCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.ORCID https://orcid.org/0000-0002-5671-2299
Jonas A Kengne-OuafoCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.
Magellan TchouakuiCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.
Murielle J WondjiCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.
Leon M J MugenziSyngenta Crop Protection, Werk Stein, Schaffhauserstrasse, Stein, Switzerland.
Jack HearnCentre for Epidemiology and Planetary Health, Scotland's Rural College (SRUC), RAVIC, Inverness, UK.
Boyomo OnanaThe University of Yaoundé 1, Yaoundé, Cameroon.
Charles S WondjiCentre for Research in Infectious Diseases (CRID), Yaoundé, Cameroon.

Funding

Gates Foundation INV-006003Wellcome TrustWellcome Trust 217188/Z/19/Z
6 · The paper itself

Abstract

Intensification of insecticide resistance in malaria vectors is undermining efforts to sustain control strategies. The evolutionary features underlying such exacerbation in major vector such as Anopheles funestus are only partially understood. PoolSeq whole genome analysis of Anopheles funestus from Mibellon (Cameroon), (alive and dead at 1×, 5× and 10× concentrations), failed to identify hits associated with resistance escalation. However, stronger signals emerge at the rp1 and CYP9 loci when comparing these phenotypes to the susceptible reference strain FANG, with genomic analysis using F

Indexed as

AnophelesInsecticide ResistancePyrethrinsAnimalsCameroonCytochrome P-450 Enzyme SystemEvolution, MolecularGenome-Wide Association StudyInsecticidesMosquito VectorsCytochrome P-450 Enzyme SystemInsecticidesPyrethrinsAnopheles funestusElizabethkingia anophelisgenomicmalariaPoolSeq

Identifiers

PMID41491590
PMCPMC12768894

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.