Evidence map›Paper›PMID 41491553›Full record

ArticleBritish journal of anaesthesia2026

Hydroxocobalamin for vasoplegia in cardiac surgery: an uncertain balance of risk and benefit. Comment on Br J Anaesth 2025; 135: 870-7.

Matthieu Legrand

Abstract readLetter
In one paragraph

Article in British journal of anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Matthieu LegrandDepartment of Anesthesia and Perioperative Care, Division of Critical Care Medicine, University of California San Francisco, San Francisco, CA, USA; INI-CRCT (Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists) Network, Nancy, France. Electronic address: matthieu.legrand@ucsf.edu.

Funding

The choice of vasopressor to prevent postoperative acute kidney injury after major non-cardiac surgery: a multicenter pragmatic cluster cross-over randomized trial (the VEGA-2 trial)R01DK139484 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SACHIN KHETERPAL, Matthieu Legrand · 2024 to 2026
$2.0M
NIDDK NIH HHS R01 DK139484
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acute kidney injurycardiac surgeryhydroxocobalaminshockvasoplegia

Identifiers

PMID41491553
PMCPMC13326626

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.