Evidence map›Paper›PMID 41491472›Full record

SynthesisBMC pediatrics2026

Association between maternal exposure to mercury during pregnancy and birth weight: a systematic review and meta-analysis.

Shuxia Zhang, Lili Li, Yanfei Zuo, Dandan Ma, Ruichun Gong, Guijie Wang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shuxia Zhang *Department of obstetrics, Dezhou Women and Children's Hospital, Dezhou, 253000, China.
Lili Li *Department of obstetrics, Dezhou Women and Children's Hospital, Dezhou, 253000, China.
Yanfei Zuo *Department of obstetrics, Xiajin County People's Hospital, Dezhou, 253200, China.
Dandan MaDepartment of obstetrics, Dezhou Women and Children's Hospital, Dezhou, 253000, China.
Ruichun GongDepartment of obstetrics, Dezhou Women and Children's Hospital, Dezhou, 253000, China.
Guijie WangDepartment of obstetrics, Dezhou Women and Children's Hospital, Dezhou, 253000, China. jie19860488@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpidemiological research has suggested that exposure to mercury in pregnancy may negatively affect birth weight (BW). However, the results were inconclusive. This meta-analysis aimed to provide a quantitative summary of evidence for the relation of prenatal mercury exposure to BW.

methodsWe performed a systematic search in the PubMed and Scopus databases until March 2024. The pooled effects of prenatal mercury exposure on birth weight (BW) were assessed using a random-effects model, using the standardized regression coefficients (β) along with their corresponding 95% confidence intervals (CI). Stratified analysis by type of specimen, sample size, method of mercury assessment, Hg concentration, and trimester of sampling was conducted to investigate possible sources of heterogeneity.

resultsForty-one studies, including 128,487 participants, were analyzed. In the overall analysis, no significant relationship was revealed between prenatal mercury exposure and BW (β= -0.002, 95%CI: -0.003 to 0.0001; P = 0.06) with substantial heterogeneity (I

conclusionThis meta-analysis revealed that mercury exposure may be negatively associated with birth weight, especially when higher concentrations are present in the blood and placenta, as well as during the late stages of pregnancy, which significantly correlates with lower neonatal BW.

Indexed as

Birth WeightMaternal ExposureMercuryFemaleHumansInfant, NewbornPregnancyMercuryBirth weightMercuryMeta-analysisPregnancy outcome

Identifiers

PMID41491472
PMCPMC12870422

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