Evidence map›Paper›PMID 41491375›Full record

ArticleInsights into imaging2026

Why we still miss breast cancers: strategies for improving mammography interpretation.

Niketa Chotai, Aishwarya Gadwal, Divya Buchireddy, Wei Tse Yang

Abstract read
In one paragraph

Article in Insights into imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Niketa ChotaiRadLink Women Imaging Center, Tan Tock Seng Hospital, Singapore, Singapore. niketachotai@gmail.com.ORCID http://orcid.org/0000-0003-4005-2123
Aishwarya GadwalDepartment of Medical Imaging, University of Toronto, Toronto, ON, Canada.
Divya BuchireddySiemens Healthineers, Mumbai, India.
Wei Tse YangDepartment of Breast Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnostic errors in mammography-particularly missed or delayed breast cancer detection-have a substantial impact on patient outcomes. These misdiagnoses remain a leading cause of malpractice claims in radiology, underscoring their serious clinical and legal implications. Contributing factors to errors in breast imaging include reader-related cognitive biases, lesion characteristics, patient-specific variables, and technical limitations. To address these challenges, a systematic approach is essential. Key strategies include structured error recognition, peer review processes, and robust quality assurance programs. Educational initiatives and system-level interventions-such as structured training, continuous feedback loops, and the integration of AI-driven computer-aided detection (CAD) tools-can significantly reduce diagnostic errors and enhance accuracy in breast imaging interpretation. This article aims to highlight common pitfalls in mammography, analyze root causes, and propose practical strategies for improvement. Real-life cases of missed diagnoses are included to reinforce key learning points and support radiologists in improving diagnostic precision and improving patient care. CRITICAL RELEVANCE STATEMENT: Missed or delayed breast cancer diagnoses stem from multiple factors. A multi-pronged strategy-combining peer review, bias mitigation, education, supportive environments, and AI tools-can improve diagnostic accuracy and enhance interpretive accuracy and advance quality standards in breast imaging practice. KEY POINTS: Missed or delayed breast cancer diagnoses on mammography continue to be a significant source of diagnostic error with serious clinical and medico-legal consequences. Contributing factors to missed or delayed breast cancer diagnoses include cognitive biases, subtle lesion characteristics, patient-specific variables, and technical limitations. Structured peer review, double reading, and robust quality assurance programs can reduce interpretive variability and improve diagnostic performance. Educational initiatives and AI-driven tools, such as computer-aided detection (CAD), support error reduction and enhance accuracy in breast imaging interpretation.

Indexed as

False negativeMammogramMissed breast cancerStrategies

Identifiers

PMID41491375
PMCPMC12770129

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.